Top > Search of International Patents > Random copolymers of oxazoline

Random copolymers of oxazoline

Foreign code F110003388
File No. A252-32WO
Posted date Jun 23, 2011
Country United States of America
Application number 99128206
Gazette No. 20090156782
Gazette No. 7732561
Date of filing Aug 30, 2006
Gazette Date Jun 18, 2009
Gazette Date Jun 8, 2010
International application number JP2006317587
International publication number WO2007026932
Date of international filing Aug 30, 2006
Date of international publication Mar 8, 2007
Priority data
  • P2005-253977 (Sep 1, 2005) JP
  • 2006WO-JP317587 (Aug 30, 2006) WO
Title Random copolymers of oxazoline
Abstract (US7732561)
The invention provides approximately monodispersible random copolymers obtained from monomeric mixtures of 2-ethyl-2-oxazoline with 2-isopropyl-2-oxazoline, production method thereof and 2-isopropyl-2-oxazoline homopolymer obtained by using special initiator.
Such polymers exhibit temperature-responsiveness in an aqueous solution within a broad temperature range, and are useful materials in the technical fields of surface chemistry and biomaterials.
Scope of claims [claim1]
1. A production method of a homopolymer represented by the following formula:
wherein R3 stands for hydrogen or C1-5 alkyl, m stands for an integer of 1-20, and n stands for an integer of 5-10,000,
which comprises a step of ring-opening polymerizing with 2-isopropyl-2-oxazoline in an inert solvent at 30 deg. C.-50 deg. C. in the presence of a cationic polymerization initiator, a step of reacting the resultant homopolymer with a nucleophilic agent, and, where necessary, a step of isolating the formed homopolymer.
[claim2]
2. The production method according to claim 1, in which the cationic polymerization initiator is a substituted or unsubstituted, straight chain or branched C1-20 alkyl tosylate.
[claim3]
3. The production method according to claim 2, in which the substituent on the substituted straight chain or branched C1-20 alkyl is represented by a formula,
or a formula,
R3C≡C -- ,
wherein R1 and R2 either stand for C1-10 alkoxy, aryloxy or aryl-C1-3 alkyloxy, independently of each other, or R1 and R2 together stand for optionally C1-5 alkyl-substituted ethylenedioxy ( -- O -- CH(R') -- CH2 -- O -- , R' being hydrogen or C1-5 alkyl) or oxy (.dbd.0) group, and
R3 stands for hydrogen or C1-5 alkyl.
[claim4]
4. A homopolymer represented by the following formula
in the formula, R3 stands for hydrogen or C1-5 alkyl, m stands for an integer of 1-20, and n stands for an integer of 5-10,000.
  • Inventor, and Inventor/Applicant
  • KATAOKA KAZUNORI
  • YAMASAKI YUICHI
  • PARK JOON-SIK
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
IPC(International Patent Classification)
Reference ( R and D project ) CREST Creation of Bio-Devices and Bio-Systems with Chemical and Biological Molecules for Medical Use AREA
Please contact us by E-mail or facsimile if you have any interests on this patent.

PAGE TOP

close
close
close
close
close
close