TOP > 外国特許検索 > Method of producing diol, polydiol, secondary alcohol or diketone compound

Method of producing diol, polydiol, secondary alcohol or diketone compound

外国特許コード F110003552
整理番号 BE06006WO
掲載日 2011年6月29日
出願国 アメリカ合衆国
出願番号 44178007
公報番号 20090240085
公報番号 7696386
出願日 平成19年9月28日(2007.9.28)
公報発行日 平成21年9月24日(2009.9.24)
公報発行日 平成22年4月13日(2010.4.13)
国際出願番号 JP2007069100
国際公開番号 WO2008038801
国際出願日 平成19年9月28日(2007.9.28)
国際公開日 平成20年4月3日(2008.4.3)
優先権データ
  • 特願2006-268796 (2006.9.29) JP
  • 特願2007-056820 (2007.3.7) JP
  • 2007WO-JP69100 (2007.9.28) WO
発明の名称 (英語) Method of producing diol, polydiol, secondary alcohol or diketone compound
発明の概要(英語) (US7696386)
The invention is a process of using, as a reducing agent, a 12CaO.7Al2O3 electride containing electrons in a number of 1019 or more and 2.3×1021 cm-3 or less in its cages to subject a carbonyl compound to reductive coupling in a solvent, thereby synthesizing a diol or polydiol.
The invention is also a process of reducing a ketone compound in a solvent, thereby synthesizing a secondary alcohol or diketone compound.
According to the process of the invention, it is possible to synthesize a diol or polydiol, or a secondary alcohol or diketone compound through simple operations in a short period without using an expensive and harmful metal hydride or metal salt nor limiting the atmosphere for the synthesis to an inert gas atmosphere as in conventional processes.
特許請求の範囲(英語) [claim1]
1. A process for producing a diol or polydiol, comprising the step of using, as a reducing agent, a 12CaO.7Al2O3 electride containing electrons in a number of 1019 cm-3 or more and 2.3 * 1021 cm-3 or less in its cages to subject a carbonyl compound to reductive coupling in water, an organic solvent, or a mixed solvent of water and an organic solvent.
[claim2]
2. The process for producing a diol or polydiol according to claim 1, wherein the carbonyl compound is a compound wherein at least one out of two substituents bonded to a carbonyl group is an aryl group.
[claim3]
3. The process for producing a diol or polydiol according to claim 1, wherein the carbonyl compound is represented by the following general formula:
wherein R1 is a functional group selected from a hydrogen atom, an alkyl group and an aryl group, R2, R3, R4, R5 and R6 are each a functional group, bonded to the aryl group, selected from a hydrogen atom, a chloro radical, a bromo radical, a iodo radical, an alkyl group, an aryl group, a carbonyl group, an allyl group, a vinyl group, an amino group, a hydroxy group, an alkoxy group, a nitro group, a cyano group, and an imino group, and R1 and the aryl group may be bonded to each other to form a ring structure.
[claim4]
4. The process for producing a diol or polydiol according to claim 1, wherein about the use amount of the 12CaO.7Al2O3 electride relative to the carbonyl compound (12CaO.7Al2O3/the carbonyl compound), the ratio by weight of the former to the latter is from 2 to 20.
[claim5]
5. The process for producing a diol or polydiol according to claim 1, wherein a reaction atmosphere for the reductive coupling is the inside of air.
[claim6]
6. A process for producing a secondary alcohol, comprising the step of using, as a reducing agent, a 12CaO.7Al2O3 electride containing electrons in a number of 1019 cm-3 or more and 2.3 * 1021 cm-3 or less in its cages to reduce a ketone compound represented by compound 1 in the following reaction equation 1 in water, an organic solvent, or a mixed solvent of water and an organic solvent, thereby synthesizing the secondary alcohol which is a secondary alcohol represented by compound 2 in the reaction equation 1:
wherein R and R1 are each a functional group selected from an aryl group and an alkyl group, and at least one of R and R1 contains an aryl group.
[claim7]
7. The process for producing a secondary alcohol according to claim 6, wherein R and R1 are each at least one selected from a methyl group, a phenyl group, a phenylcyano group, or a phenylmethoxy group, except that R and R1 are simultaneously methyl groups.
[claim8]
8. The process for producing a secondary alcohol according to claim 6, wherein the organic solvent, or the organic solvent of the mixed solvent is dioxane.
[claim9]
9. The process for producing a secondary alcohol according to claim 6, wherein about the use amount of the 12CaO.7Al2O3 electride relative to the ketone compound (12CaO.7Al2O3/the ketone compound), the ratio by weight of the former to the latter is from 2 to 20.
[claim10]
10. The process for producing a secondary alcohol according to claim 6, wherein an atmosphere for the reaction is the inside of the air.
[claim11]
11. A process for producing a dianthrone, comprising the step of using, as a reducing agent, a 12CaO.7Al2O3 electride containing electrons in a number of 1019 cm-3 or more and 2.3 * 1021 cm-3 or less in its cages to dimerize an arylketone compound (anthrone) represented by compound 3 in the following reaction equation 2 in a mixed solvent of water and an organic solvent, thereby synthesizing the dianthrone which is a dianthrone represented by compound 4 in the reaction equation 2:
[claim12]
12. The process for producing a dianthrone according to claim 11, wherein the organic solvent is selected from CH3CN, Et-OH, t-Bu-OH, or dioxane.
[claim13]
13. The process for producing a dianthrone according to claim 11, wherein an atmosphere for the reaction is the inside of an inert gas.
[claim14]
14. A process for producing a dichalcone mixture, comprising the step of using, as a reducing agent, a 12CaO.7Al2O3 electride containing electrons in a number of 1019 cm-3 or more and 2.3 * 1021 cm-3 or less in its cages to dimerize a ketone compound represented by compound 5 in the following reaction equation 3 (chalcone), which contains a carbon double bond, in a mixed solvent of water and an organic solvent, thereby synthesizing dichalcones represented by compound 6 and compound 7 in the reaction equation 3:
[claim15]
15. The process for producing a dichalcone according to claim 14, wherein the organic solvent is tetrahydrofuran (THF).
  • 発明者/出願人(英語)
  • HOSONO HIDEO
  • BUCHAMMAGARI HARITHA
  • TODA YOSHITAKE
  • HIRANO MASAHIRO
  • OSAKADA KOHTARO
  • TAKEUCHI DAISUKE
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
国際特許分類(IPC)
参考情報 (研究プロジェクト等) ERATO/SORST Exploring and developing applications for active functions utilizing nanostructure embedded in transparent oxides AREA
ライセンスをご希望の方、特許の内容に興味を持たれた方は、問合せボタンを押してください。

PAGE TOP

close
close
close
close
close
close