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METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN

Foreign code F110004018
File No. K02216WO
Posted date Jul 8, 2011
Country EPO
Application number 08790313
Gazette No. 2177611
Gazette No. 2177611
Date of filing Jul 30, 2008
Gazette Date Apr 21, 2010
Gazette Date Nov 20, 2013
International application number WO2008JP02049
Date of international filing Jul 30, 2008
Priority data
  • P2007-201147 (Aug 1, 2007) JP
Title METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN
Abstract

The object of the present invention is to provide a detection method that can detect an antigen even if the target antigen has a low molecular weight in a simpler, more efficient, and more stable manner and with higher sensitivity. The detection of the antigen is carried out by using a fusion protein comprising a polypeptide containing a V H domain of an antibody

a given protein

a linker peptide

a partner protein having an activity of binding to the protein and capable of detecting binding to the protein

and a polypeptide containing a V L domain of the antibody

in this order or in inverse order to this order, wherein the presence or absence of the binding of the polypeptide containing a V H domain and the polypeptide containing a V L domain to the antigen induces the presence or absence of the binding of the protein and the partner protein.

  • Applicant
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • Inventor
  • UEDA, HIROSHI
  • KOJIMA, MIKI
IPC(International Patent Classification)
Reference ( R and D project ) PRESTO Structure Function and Measurement Analysis AREA
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