Top > Search of International Patents > ACETYLLYSINE-RECOGNIZING MONOCLONAL ANTIBODY AND PROCESS FORPRODUCING THE SAME

ACETYLLYSINE-RECOGNIZING MONOCLONAL ANTIBODY AND PROCESS FORPRODUCING THE SAME achieved

Foreign code F110004296
File No. A131-07CA
Posted date Jul 13, 2011
Country Canada
Application number 2441187
Gazette No. 2441187
Gazette No. 2441187
Date of filing Mar 13, 2002
Gazette Date Sep 26, 2002
Gazette Date Feb 10, 2009
Priority data
  • P2001-074263 (Mar 15, 2001) JP
Title ACETYLLYSINE-RECOGNIZING MONOCLONAL ANTIBODY AND PROCESS FORPRODUCING THE SAME achieved
Abstract

Anti-acetyllysine monoclonal antibody capable of recognizing N.epsilon.- acetyllysine regardless of the types of the adjacent amino acids. Namely, a monoclonal antibody having a light chain comprising a constant region having the amino acid sequence represented by SEQ ID NO:1 and a variable region having the amino acid sequence represented by SEQ ID NO:2 or an amino acid sequence derived from this amino acid sequence by deletion, substitution or addition of one to several amino acids, and a heavy chain comprising a constant region having the amino acid sequence represented by SEQ ID NO:3 an d a variable region having the amino acid sequence represented by SEQ ID NO:4 or an amino acid sequence derived from this amino acid sequence by deletion, substitution or addition of one to several amino acids, and being capable of recognizing N.epsilon.-acetyllysine in a protein regardless of the types of the adjacent amino acids, i.e., being capable of accepting adjacent amino acids over a broad range

and a process for producing this monoclonal antibo dy characterized by using a chemically acetylated protein as an antigen.</SDOAB >

  • Applicant
  • JAPAN SCIENCE AND TECHNOLOGY CORPORATION
  • Inventor
  • KOMATSU, YASUHIKO,
  • YOSHIDA, MINORU
IPC(International Patent Classification)
Reference ( R and D project ) CREST Structure and Function of Genomes AREA
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