PROTEIN NECTIN-3

• 特願2000-065595 (2000.3.9) JP

Proteins nectin-3 having the amino acid sequences represented by SEQ ID NOS: 2, 4 and 6 which are novel proteins belonging to the nectin protein family participating in the adhesion between cells

polynucleotides encoding these proteins nectin-3 and having the base sequences respectively represented by SEQ ID NOS:1, 3 and 5

recombinant vectors having these polynucleotides

and antibodies against the above-described proteins nectin-3. The proteins necti n- 3 not only provide important information in clarifying the whole molecular mechanism of cell adhesion but potentially relate to the clarification of, f or example, the infiltration and metastasis mechanisms of cancer, thereby being useful in diagnosing the malignancy of cancer, developing methods of preventing and treating the same and remedies, etc. therefor.

• JAPAN SCIENCE AND TECHNOLOGY CORPORATION,
• TAKAHASHI, KENICHI

• TAKAI, YOSHIMI,
• TAKAHASHI, KENICHI,
• SATO, KEIKO,
• NAKANISHI, HIROYUKI

• C12N  15/12      動物蛋白質をコードする遺伝子
• C07K  14/78      結合組織ペプチド，例．コラーゲン，エラスチン，ラミニン，フィブロネクチン，ビトロネクチン，低温不溶性グロブリン（ＣＩＧ）
• C07K  16/18      動物またはヒトからの物質に対するもの