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Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome

Foreign code F110004587
File No. K02303WO
Posted date Jul 20, 2011
Country China
Application number 200880117473
Gazette No. 101873866
Gazette No. 101873866
Date of filing Nov 21, 2008
Gazette Date Oct 27, 2010
Gazette Date Oct 16, 2013
Priority data
  • P2007-305122 (Nov 26, 2007) JP
Title Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome
Abstract

The object is to provide: a therapeutic or prophylactic agent for metabolic syndrome, which has improved stability in a living body

and others. The therapeutic or prophylactic agent for metabolic syndrome comprises, as an active ingredient, DNA that encodes receptor activity-modifying protein (RAMP) 2 and is selected from the items (a) to (d) below or a polypeptide encoded by the DNA: (a) DNA which has the nucleotide sequence depicted in SEQ ID NO:1

(b) DNA which has a nucleotide sequence capable of hybridizing with the nucleotide sequence depicted in SEQ ID NO:1 under stringent conditions

(c) DNA which has a nucleotide sequence encoding an amino acid sequence having the substitution, deletion and/or addition of one or more amino acid residues in the amino acid sequence depicted in SEQ ID NO:2

and (d) DNA which has a nucleotide sequence having a 90% or more homology with the nucleotide sequence depicted in SEQ ID NO:1.

  • Applicant
  • JAPAN SCIENCE & TECH AGENCY
  • Inventor
  • SHINDO TAKAYUKI
IPC(International Patent Classification)
Reference ( R and D project ) PRESTO Metabolism and Cellular Function AREA
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