Therapeutic drug using antibody-presenting hollowprotein nanoparticles and hollow protein nanoparticles
|Posted date||Jul 28, 2011|
|Country||Republic of Korea|
|Date of filing||Sep 24, 2004|
|Gazette Date||Dec 16, 2004|
|Gazette Date||Oct 12, 2006|
|International application number||PCT/JP2003/003694|
|International publication number||WO2003/082330|
|Date of international filing||Mar 26, 2003|
|Date of international publication||Oct 9, 2003|
|Title||Therapeutic drug using antibody-presenting hollowprotein nanoparticles and hollow protein nanoparticles|
As the medicament using the protein hollow nano particle presented the antibody to the specific cell or the organization, treatment method using the medicine and this medicine in which the animal experiment recognizes the therapeutic effect in fact are provided. In the hollow nano particle consisting of protein (the HBsAg which for example is mutated in order to be the infection nature which confronts the original the cell going sterile and is mutated in order to additionally present the antibody) having the ability to form grains, the cell introduction material (the herpes simplex virus originated thymidine kinase gene called for example, the gene for the cancer treatment) for the disease treating is included. The antibody including the cancer specific antibody etc. is indicated in the particle's surface described in the above. Recognizes clearly the molecule existing in the specific cancer cell surface as the antigen.
The cell introduction material for the protein having the protein hollow nano particle, the antibody presentation, and the ability to form grains, the mutation, deletion, the disease treating.
|IPC(International Patent Classification)|
Contact Information for " Therapeutic drug using antibody-presenting hollowprotein nanoparticles and hollow protein nanoparticles "
- Japan Science and Technology Agency Department of Intellectual Property Management
- URL: http://www.jst.go.jp/chizai/
- Address: 5-3, Yonbancho, Chiyoda-ku, Tokyo, Japan , 102-8666
- Fax: 81-3-5214-8476