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High-stability optical microscope

Foreign code F110005026
File No. A021-22WO
Posted date Aug 17, 2011
Country United States of America
Application number 50610702
Gazette No. 20050117204
Gazette No. 7307784
Date of filing Sep 3, 2002
Gazette Date Jun 2, 2005
Gazette Date Dec 11, 2007
International application number JP2002008935
International publication number WO2003079089
Date of international filing Sep 3, 2002
Date of international publication Sep 25, 2003
Priority data
  • P2002-073455 (Mar 18, 2002) JP
  • 2002WO-JP08935 (Sep 3, 2002) WO
Title High-stability optical microscope
Abstract (US7307784)
This invention provides a highly stable optical microscope that prevents drift and makes it possible to record images or take measurements for several hours with accuracy in the order of nanometers.
The highly stable optical microscope of this invention includes the support structure ( 41 ) that accommodates and supports components including the optical imaging system, straight tube ( 28 ) that accommodates and supports components including the optical photometric system, and support structure ( 7 ) that accommodates and supports components including the illumination system.
These support structures have a hollow pyramid or conical shape with a low center of gravity.
The highly stable optical microscope of this invention features the objective lenses, imaging lenses, optical imaging and photometric systems that are mounted, forming a straight line, on the supporting structures that are symmetrical about the optical axis in both shape and mass.
Scope of claims [claim1]
1. A highly stable optical microscope, wherein an objective lens, an imaging lens, an optical imaging and a photometric system are mounted without deviation, forming one single straight line, on a straight guide mechanism and a hollow support structure, surrounding the straight guide mechanism, that are symmetrical about an optical axis in both shape and mass;
and
the support structure for the optical imaging and photometric system is a square truncated pyramid or a circular truncated cone to prevent changes in inclination due to temperature fluctuations and vibration.
[claim2]
2. The highly stable optical microscope as claimed in claim 1, wherein a sample base and the objective lens, arranged symmetrically in shape and mass about the optical axis, are integrated and supported by support structures that are independent of all imaging lenses and are integrated at a low center of gravity close to a vibration isolating table.
[claim3]
3. The highly stable optical microscope as claimed in claim 1, wherein in an infinity corrected optical microscope, a half mirror and the imaging lens are combined and mounted at the inlet of an optical illumination system and an optical monitor system respectively, andwherein the optical illumination system is a combination of at least an incident-light fluorescence, a total internal reflection fluorescence, a transmitted light fluorescence, an incident polarized light, a transmitted polarized light, a bright field incidence, and an optical tweezer.
[claim4]
4. The highly stable optical microscope as claimed in claim 3, wherein a sample base and the objective lens, arranged symmetrically in shape and mass about the optical axis, are integrated and supported by support structure that is independent of all imaging lenses and is integrated at a low center of gravity close to a vibration isolating table.
[claim5]
5. The highly stable optical microscope as claimed in claim 3, wherein the half mirror is a dichroic mirror.
[claim6]
6. A highly stable optical microscope, wherein an objective lens, an imaging lens, an optical imaging and a photometric system are mounted without deviation, while forming a straight line, on a straight guide mechanism and a hollow support structure that are symmetrical about an optical axis in both shape and mass,wherein a sample base and the objective lens, arranged symmetrically in shape and mass about the optical axis, are integrated and supported by support structures that are independent of all imaging lenses and are integrated at a low center of gravity close to a vibration isolating table;
wherein a half mirror and the imaging lens are combined and mounted at the inlet of an optical illumination system and an optical monitor system respectively, the half mirror being dichroic mirror;
and
wherein the optical illumination system is a combination of at least an incident-light fluorescence, a total internal reflection fluorescence, a transmitted light fluorescence, an incident polarized light, a transmitted polarized light, a bright field incidence, and an optical tweezer.
  • Inventor, and Inventor/Applicant
  • KINOSHITA KAZUHIKO
  • SHIO MEGUMU
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
IPC(International Patent Classification)
Reference ( R and D project ) CREST Genetic Programming AREA
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