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Hapten compound and antibody

Foreign code F110005623
File No. RX03P55WO
Posted date Sep 9, 2011
Country United States of America
Application number 28053806
Gazette No. 20090317920
Gazette No. 8865874
Date of filing Oct 5, 2006
Gazette Date Dec 24, 2009
Gazette Date Oct 21, 2014
International application number JP2006319977
International publication number WO2007097065
Date of international filing Oct 5, 2006
Date of international publication Aug 30, 2007
Priority data
  • P2006-046950 (Feb 23, 2006) JP
  • 2006WO-JP319977 (Oct 5, 2006) WO
Title Hapten compound and antibody
Abstract (US8865874)
The present invention is a compound having a structure represented by the following formula (1): and an antibody to BSH obtained by using the compound as a hapten and using a complex of the hapten and a high-molecular compound as an antigen.
By using the present invention, it becomes possible to provide a hapten compound for preparing an antibody recognizing BSH highly sensitively and highly selectively, an antibody to BSH, as well as a kit for measuring BSH and an immunological measuring method having high sensitivity and excellent in quantitative property using the antibody.
Scope of claims [claim1]
1. A hybridoma producing a monoclonal antibody, wherein the hybridoma is BSF-2 (accession number FERM BP-10689).
[claim2]
2. A monoclonal antibody produced by the hybridoma BSF-2 (accession number FERM BP-I0689).
[claim3]
3. A monoclonal antibody to mercaptoundecahydrododecaborate (BSH), wherein the heavy chain of the antibody has at least 90% homology to SEQ ID NO:3 and the light chain of the antibody has at least 90% homology to SEQ ID NO:4.
[claim4]
4. A kit for measuring mercaptoundecahydrodecaborate (BSH), comprising a monoclonal antibody as defined in claim 3.
  • Inventor, and Inventor/Applicant
  • KIRIHATA MITSUNORI
  • ASANO TOMOYUKI
  • UEHARA KOHKI
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • OSAKA PREFECTURE UNIVERSITY
  • STELLA CHEMIFA
IPC(International Patent Classification)
U.S. Cl./(Sub)
  • C07F005/02D
  • C07K016/44
  • G01N033/53F
  • G01N033/84
  • G01N033/94
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