CHOLESTEROL-EFFLUX PEPTIDE

外国特許コード	F110005871
整理番号	S2011-0369-N0
掲載日	2011年11月9日
出願国	世界知的所有権機関（ＷＩＰＯ）
国際出願番号	2010JP065070
国際公開番号	WO 2011/027839
国際出願日	平成22年9月2日(2010.9.2)
国際公開日	平成23年3月10日(2011.3.10)
優先権データ	特願2009-202273 (2009.9.2) JP
発明の名称 （英語）	CHOLESTEROL-EFFLUX PEPTIDE
発明の概要（英語）	Disclosed is a peptide which has an effect of promoting cholesterol efflux and another effect of generating HDL. This cholesterol-efflux peptide has an effect of generating HDL in addition to the effect of promoting cholesterol efflux. A medicinal composition that comprises the aforesaid cholesterol-efflux peptide as the main active ingredient is useful in promoting cholesterol efflux, increasing serum HDL concentration, activating LCAT and promoting RCT and, therefore, can be used for preventing and treating cardiovascular diseases, for example, angina, hypertension, hyperlipemia such as hypercholesterolemia and arterial sclerosis such as atherosclerosis, cardiovascular diseases relating to cardiovascular disorders that are induced by medical treatments using a balloon, a stent or the like such as re-stenosis caused by atherosclerotic plaque, and disorders related thereto.
出願人（英語） ※2012年7月以前掲載分については米国以外のすべての指定国	Fukuoka University
発明者（英語）	SAKU Keijiro ANDO Setsuko UEHARA Yoshinari
国際特許分類(IPC)	C07K  14/775     アポリポペプチド A61K  38/00      ペプチドを含有する医療製剤 A61P   3/06      高脂血症治療剤 A61P   9/10      虚血，アテローム性動脈硬化症の治療のためのもの，例．抗アンギナ，冠状動脈拡張剤，心筋梗塞，網膜症，脳血流障害，腎臓細動脈硬 C07K  19/00      ハイブリッドペプチド
指定国	AE(UTILITY MODEL),AG,AL(UTILITY MODEL),AM(PROVISIONAL PATENT)(UTILITY MODEL),AO(UTILITY MODEL),AT(UTILITY MODEL),AU,AZ(UTILITY MODEL),BA,BB,BG(UTILITY MODEL),BH(UTILITY MODEL),BR(UTILITY MODEL),BW,BY(UTILITY MODEL),BZ(UTILITY MODEL),CA,CH,CL(UTILITY MODEL),CN(UTILITY MODEL),CO(UTILITY MODEL),CR(UTILITY MODEL),CU(INVENTOR'S CERTIFICATE),CZ(UTILITY MODEL),DE(UTILITY MODEL),DK(UTILITY MODEL),DM,DO(UTILITY MODEL),DZ,EC(UTILITY MODEL),EE(UTILITY MODEL),EG(UTILITY MODEL),ES(UTILITY MODEL),FI(UTILITY MODEL),GB,GD,GE(UTILITY MODEL),GH(UTILITY CERTIFICATE),GM,GT(UTILITY MODEL),HN(UTILITY MODEL),HR(CONSENSUAL PATENT),HU(UTILITY MODEL),ID,IL,IN,IS,JP(UTILITY MODEL),KE(UTILITY MODEL),KG(UTILITY MODEL),KM,KN,KP(INVENTOR'S CERTIFICATE)(UTILITY MODEL),KR(UTILITY MODEL),KZ(PROVISIONAL PATENT)(UTILITY MODEL),LA,LC,LK,LR,LS(UTILITY MODEL),LT,LU,LY,MA,MD(UTILITY MODEL),ME,MG,MK,MN,MW,MX(UTILITY MODEL),MY(UTILITY-INNOVATION),MZ(UTILITY MODEL),NA,NG,NI(UTILITY MODEL),NO,NZ,OM(UTILITY MODEL),PE(UTILITY MODEL),PG,PH(UTILITY MODEL),PL(UTILITY MODEL),PT(UTILITY MODEL),RO,RS(PETTY PATENT),RU(UTILITY MODEL),SC,SD,SE,SG,SK(UTILITY MODEL),SL(UTILITY MODEL),SM,ST,SV(UTILITY MODEL),SY,TH(PETTY PATENT),TJ(UTILITY MODEL),TM(PROVISIONAL PATENT),TN,TR(UTILITY MODEL),TT(UTILITY CERTIFICATE),TZ,UA(UTILITY MODEL),UG(UTILITY CERTIFICATE),US,UZ(UTILITY MODEL),VC(UTILITY CERTIFICATE),VN(PATENT FOR UTILITY SOLUTION),ZA,ZM,ZW,EP(AL,AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,SE,SI,SK,SM,TR),OA(BF(UTILITY MODEL),BJ(UTILITY MODEL),CF(UTILITY MODEL),CG(UTILITY MODEL),CI(UTILITY MODEL),CM(UTILITY MODEL),GA(UTILITY MODEL),GN(UTILITY MODEL),GQ(UTILITY MODEL),GW(UTILITY MODEL),ML(UTILITY MODEL),MR(UTILITY MODEL),NE(UTILITY MODEL),SN(UTILITY MODEL),TD(UTILITY MODEL),TG(UTILITY MODEL)),AP(BW(UTILITY MODEL),GH(UTILITY MODEL),GM(UTILITY MODEL),KE(UTILITY MODEL),LR(UTILITY MODEL),LS(UTILITY MODEL),MW(UTILITY MODEL),MZ(UTILITY MODEL),NA(UTILITY MODEL),SD(UTILITY MODEL),SL(UTILITY MODEL),SZ(UTILITY MODEL),TZ(UTILITY MODEL),UG(UTILITY MODEL),ZM(UTILITY MODEL),ZW(UTILITY MODEL)),EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM)