TRANSGENIC BIRD CAPABLE OF EXPRESSING .alpha.-GALACTOSE EPITOPE, VIRUS, AND VACCINE
| Foreign code | F110005891 |
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| File No. | S2009-1181-C0 |
| Posted date | Nov 9, 2011 |
| Country | WIPO |
| International application number | 2010JP067083 |
| International publication number | WO 2011/040527 |
| Date of international filing | Sep 30, 2010 |
| Date of international publication | Apr 7, 2011 |
| Priority data |
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| Title |
TRANSGENIC BIRD CAPABLE OF EXPRESSING .alpha.-GALACTOSE EPITOPE, VIRUS, AND VACCINE
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| Abstract | Disclosed are: a means for expressing .alpha.-Gal in a virus without using any enzyme; the production of a virus having .alpha.-Gal expressed therein by utilizing the means; the production of a vaccine from the virus; an influenza virus vaccine having a high effect (antigenicity), which is produced using a virus having enhanced immune response to a virus; and others. Specifically disclosed are: a transgenic bird which can express an .alpha.-galactose epitope (Gal.alpha.1-3Gal.beta.1-4GlcNAc-R: referred to as ".alpha.-Gal", hereinafter), wherein the bird is a chicken and may be G0 or a progeny thereof; a method for producing a transgenic bird, which comprises introducing a vector that is used for the introduction of an .alpha.1,3-galactose transferase (.alpha.1,3-GT) gene and contains an .alpha.1,3-GT gene in such a manner that the gene can be expressed, into a bird, thereby producing the transgenic bird; a biological sample, such as an egg, obtained from the transgenic bird; and a method for producing an .alpha.-Gal-expressing virus, which comprises inoculating a biological sample with a virus, cultivating the biological sample that has been inoculated with the virus, and obtaining a virus capable of expressing .alpha.-Gal from the cultivated biological sample. |
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| IPC(International Patent Classification) |
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| Specified countries | AE(UTILITY MODEL),AG,AL(UTILITY MODEL),AM(PROVISIONAL PATENT)(UTILITY MODEL),AO(UTILITY MODEL),AT(UTILITY MODEL),AU,AZ(UTILITY MODEL),BA,BB,BG(UTILITY MODEL),BH(UTILITY MODEL),BR(UTILITY MODEL),BW,BY(UTILITY MODEL),BZ(UTILITY MODEL),CA,CH,CL(UTILITY MODEL),CN(UTILITY MODEL),CO(UTILITY MODEL),CR(UTILITY MODEL),CU(INVENTOR'S CERTIFICATE),CZ(UTILITY MODEL),DE(UTILITY MODEL),DK(UTILITY MODEL),DM,DO(UTILITY MODEL),DZ,EC(UTILITY MODEL),EE(UTILITY MODEL),EG(UTILITY MODEL),ES(UTILITY MODEL),FI(UTILITY MODEL),GB,GD,GE(UTILITY MODEL),GH(UTILITY CERTIFICATE),GM,GT(UTILITY MODEL),HN(UTILITY MODEL),HR(CONSENSUAL PATENT),HU(UTILITY MODEL),ID,IL,IN,IS,JP(UTILITY MODEL),KE(UTILITY MODEL),KG(UTILITY MODEL),KM,KN,KP(INVENTOR'S CERTIFICATE)(UTILITY MODEL),KR(UTILITY MODEL),KZ(PROVISIONAL PATENT)(UTILITY MODEL),LA,LC,LK,LR,LS(UTILITY MODEL),LT,LU,LY,MA,MD(UTILITY MODEL),ME,MG,MK,MN,MW,MX(UTILITY MODEL),MY(UTILITY-INNOVATION),MZ(UTILITY MODEL),NA,NG,NI(UTILITY MODEL),NO,NZ,OM(UTILITY MODEL),PE(UTILITY MODEL),PG,PH(UTILITY MODEL),PL(UTILITY MODEL),PT(UTILITY MODEL),RO,RS(PETTY PATENT),RU(UTILITY MODEL),SC,SD,SE,SG,SK(UTILITY MODEL),SL(UTILITY MODEL),SM,ST,SV(UTILITY MODEL),SY,TH(PETTY PATENT),TJ(UTILITY MODEL),TM(PROVISIONAL PATENT),TN,TR(UTILITY MODEL),TT(UTILITY CERTIFICATE),TZ,UA(UTILITY MODEL),UG(UTILITY CERTIFICATE),US,UZ(UTILITY MODEL),VC(UTILITY CERTIFICATE),VN(PATENT FOR UTILITY SOLUTION),ZA,ZM,ZW,EP(AL,AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HR,HU,IE,IS,IT,LT,LU,LV,MC,MK,MT,NL,NO,PL,PT,RO,SE,SI,SK,SM,TR),OA(BF(UTILITY MODEL),BJ(UTILITY MODEL),CF(UTILITY MODEL),CG(UTILITY MODEL),CI(UTILITY MODEL),CM(UTILITY MODEL),GA(UTILITY MODEL),GN(UTILITY MODEL),GQ(UTILITY MODEL),GW(UTILITY MODEL),ML(UTILITY MODEL),MR(UTILITY MODEL),NE(UTILITY MODEL),SN(UTILITY MODEL),TD(UTILITY MODEL),TG(UTILITY MODEL)),AP(BW(UTILITY MODEL),GH(UTILITY MODEL),GM(UTILITY MODEL),KE(UTILITY MODEL),LR(UTILITY MODEL),LS(UTILITY MODEL),MW(UTILITY MODEL),MZ(UTILITY MODEL),NA(UTILITY MODEL),SD(UTILITY MODEL),SL(UTILITY MODEL),SZ(UTILITY MODEL),TZ(UTILITY MODEL),UG(UTILITY MODEL),ZM(UTILITY MODEL),ZW(UTILITY MODEL)),EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM) |
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Contact Information for " TRANSGENIC BIRD CAPABLE OF EXPRESSING .alpha.-GALACTOSE EPITOPE, VIRUS, AND VACCINE "
- Obihiro University of Agriculture and Veterinary Medicine Research and International Affairs Section
- URL: http://www.obihiro.ac.jp/english/
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E-mail:
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