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Method for production of antibody using ostrich achieved

Foreign code F120006718
File No. RX03P45US2
Posted date May 28, 2012
Country United States of America
Application number 201113210512
Gazette No. 20110301336
Gazette No. 8815244
Date of filing Aug 16, 2011
Gazette Date Dec 8, 2011
Gazette Date Aug 26, 2014
International application number JP2006316960
International publication number WO2007026689
Date of international filing Aug 29, 2006
Date of international publication Mar 8, 2007
Priority data
  • P2005-246993 (Aug 29, 2005) JP
  • 2006WO-JP316960 (Aug 29, 2006) WO
  • 2008US-12065072 (Feb 27, 2008) US
Title Method for production of antibody using ostrich achieved
Abstract (US8815244)
Disclosed is an antibody produced using an ostrich.
Also disclosed is a method for producing the antibody.
By using an ostrich, it becomes possible to produce antibodies (particularly antibodies for medical use), which have been hardly produced by using the mammals such as the mouse and the rat, homogeneously in a single body, in large quantities and in a simple manner.
The method can overcome a disadvantage of lot-to-lot variation which may occur in the production of polyclonal antibodies using other animals.
Scope of claims [claim1]
1. A method of producing an ostrich antibody having binding specificity for a viral protein or a peptide thereof, comprising the steps of: a. administering to an ostrich of 2.5 to 10 months of age a viral protein or a peptide fragment thereof as an antigen,
b. permitting in vivo production of an ostrich antibody against the protein or the peptide fragment thereof, where the ostrich antibody specifically binds to the protein or the peptide fragment thereof,
c. isolating the ostrich antibody from an ostrich fluid, and
d. producing a polyclonal antibody having binding specificity for a viral protein or a peptide thereof.
[claim2]
2. The method of producing an ostrich antibody of claim 1, wherein the ostrich is female ostrich and the ostrich fluid is a yolk of an egg from the female ostrich.
  • Inventor, and Inventor/Applicant
  • TSUKAMOTO YASUHIRO
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • OSAKA PREFECTURE UNIVERSITY
IPC(International Patent Classification)
U.S. Cl./(Sub)
  • C07K016/00
  • C07K016/10
  • C07K016/18
  • C07K016/28A
  • C07K016/28C
  • K61K039/505
  • M07K317/230
  • M07K317/760
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