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COMPOSITIONS CONTAINING ANTISENSE OLIGONUCLEOTIDE TO MICRO RNA

Foreign code F120006756
File No. S2010-1236
Posted date Jun 7, 2012
Country WIPO
International application number 2011JP075924
International publication number WO 2012/063894
Date of international filing Nov 10, 2011
Date of international publication May 18, 2012
Priority data
  • P2010-254021 (Nov 12, 2010) JP
Title COMPOSITIONS CONTAINING ANTISENSE OLIGONUCLEOTIDE TO MICRO RNA
Abstract Provided are compositions which contain an antisense oligonucleotide to a micro RNA and are capable of inhibiting the growth of cancer cells. One embodiment of the present invention relates to a composition for inhibiting the growth of human cancer cells, said composition containing an antisense oligonucleotide to a micro RNA wherein said micro RNA is selected from the group consisting of hsa-miR-133a, hsa-miR-133b, hsa-miR-346 and hsa-miR-361-3p. Another embodiment of the present invention relates to a composition for inhibiting the growth of human head and neck cancer cells, said composition containing an antisense oligonucleotide to a micro RNA wherein said micro RNA is selected from the group consisting of hsa-miR-92a, hsa-miR-133a, hsa-miR-133b, hsa-miR-139-5p, hsa-miR-197, hsa-miR-328, hsa-miR-346, hsa-miR-361-3p, hsa-miR-605, hsa-miR-766, hsa-miR-1228, hsa-miR-1252, hsa-miR-1260 and hsa-miR-1271.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION EHIME UNIVERSITY
  • Inventor
  • NAKASHIRO Koichi
  • HAMAKAWA Hiroyuki
  • TANAKA Hiroshi
IPC(International Patent Classification)
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