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MEDICINAL AGENT AND BEVERAGE/FOOD FOR PREVENTING CEREBRAL DYSFUNCTION AND IMPROVING SAME meetings

Foreign code F120006801
File No. S2012-0063-N0
Posted date Jul 3, 2012
Country WIPO
International application number 2011JP002393
International publication number WO 2011/132435
Date of international filing Apr 22, 2011
Date of international publication Oct 27, 2011
Priority data
  • P2010-098602 (Apr 22, 2010) JP
Title MEDICINAL AGENT AND BEVERAGE/FOOD FOR PREVENTING CEREBRAL DYSFUNCTION AND IMPROVING SAME meetings
Abstract

Disclosed is a means for improving the symptoms of a cerebral dysfunction. The present inventors made a new discovery that the activity of brain aromatic monoamines increases when sepiapterin is administered peripherally. Disclosed, therefore, is a medicinal agent, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Also disclosed is a beverage/food, which contains at least sepiapterin or a salt thereof, for preventing or improving cerebral dysfunction. Unlike tetrahydrobiopterin and the like, sepiapterin can control reductions in the brain neuron levels of brain aromatic monoamines (serotonin, dopamine, noradrenaline, and the like) and increase the activity thereof even when administered peripherally. Therefore, sepiapterin may be effective for cerebral dysfunctions, which are due to reductions in the brain neuron levels of brain aromatic monamines, such as depression, bulimia, autism, impaired consciousness and concentration, cognitive disorders and other central mental disorders, as well as myotonia, rigidity, tremors, and other central motor disorders.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NIHON UNIVERSITY,
  • HASEGAWA, HIROYUKI,
  • AIZAWA, SHIN
  • Inventor
  • HASEGAWA, HIROYUKI,
  • AIZAWA, SHIN
IPC(International Patent Classification)
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