TOP > 外国特許検索 > CHOLESTEROL-DEPENDENT CYTOLYSIN VARIANT AND USE THEREOF IN DDS
The present invention provides a carrier whereby a drug capsule encapsulating a drug can be efficiently and very safely delivered to and incorporated into a variety of target cells or tissues, and also provides a drug delivery system in which the carrier is used. In the carrier, a cell- or tissue-specific antibody is bound to an antibody-binding domain of this cholesterol-dependent cytolysin variant. A cholesterol-containing microcapsule or functional cell packed with a medicinal ingredient or physiologically active substance serving as a carried material can be bound, via a domain (4) of the variant.
