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AGENT FOR IMPROVING EFFICIENCY OF GENERATING INDUCED PLURIPOTENT STEM CELLS AND EFFICIENT METHOD FOR GENERATING INDUCED PLURIPOTENT STEM CELLS BY USING SAME

Foreign code F120006934
File No. S2011-0314
Posted date Oct 11, 2012
Country WIPO
International application number 2012JP057455
International publication number WO 2012/128343
Date of international filing Mar 23, 2012
Date of international publication Sep 27, 2012
Priority data
  • P2011-066827 (Mar 24, 2011) JP
Title AGENT FOR IMPROVING EFFICIENCY OF GENERATING INDUCED PLURIPOTENT STEM CELLS AND EFFICIENT METHOD FOR GENERATING INDUCED PLURIPOTENT STEM CELLS BY USING SAME
Abstract

The present invention provides a method for improving the efficiency of generating iPS cells, the method involving bringing into contact, with somatic cells, one or more compounds selected from the group consisting of phenylcyclopropylamine derivatives, phenylalkyl hydrazine compounds such as the MAO inhibitor phenelzine, which is an antidepressant, and pharmaceutically acceptable salts, solvates and prodrugs thereof during the step of nucleus initialization.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY,
  • KYOTO UNIVERSITY,
  • MIYATA, NAOKI,
  • SUZUKI, TAKAYOSHI,
  • NAKAGAWA, MASATO
  • Inventor
  • MIYATA, NAOKI,
  • SUZUKI, TAKAYOSHI,
  • NAKAGAWA, MASATO
IPC(International Patent Classification)
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