Top > Search of International Patents > METHOD FOR REMOVING TUMORIGENESIS-CAUSING CELLS AMONG STEM CELLS

METHOD FOR REMOVING TUMORIGENESIS-CAUSING CELLS AMONG STEM CELLS

Foreign code F120006938
File No. S2011-0583
Posted date Oct 17, 2012
Country WIPO
International application number 2012JP058414
International publication number WO 2012/133674
Date of international filing Mar 29, 2012
Date of international publication Oct 4, 2012
Priority data
  • P2011-073690 (Mar 29, 2011) JP
Title METHOD FOR REMOVING TUMORIGENESIS-CAUSING CELLS AMONG STEM CELLS
Abstract

The present invention provides a lethal agent for undifferentiated cells and/or cells that would cause tumorigenesis, the lethal agent containing a virus vector in which a promoter for a nucleic acid for encoding an essential factor for replicating or assembling at least one virus has been replaced with a promoter for a gene which is specifically expressed in cancer cells or undifferentiated cells. The present invention further provides a lethal agent for undifferentiated cells and/or cells that would cause tumorigenesis, the lethal agent containing an expression vector including a nucleic acid for encoding a cytotoxic factor under the control of a promoter for a gene which is specifically expressed in cancer cells or undifferentiated cells. The present invention additionally provides a method for producing differentiated cells having a reduced risk of tumorigenesis, the method being characterized in that an aforesaid drug is brought into contact with a cell population induced to differentiate from stem cells, to thereby kill the undifferentiated cells or cells that would cause tumorigenesis remaining within the cell population.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • KAGOSHIMA UNIVERSITY,
  • KOSAI, KEN-ICHIRO,
  • MITSUI, KAORU
  • Inventor
  • KOSAI, KEN-ICHIRO,
  • MITSUI, KAORU
IPC(International Patent Classification)
Please contact us by E-mail if you have any interests on this patent.

PAGE TOP

close
close
close
close
close
close