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PHARMACEUTICAL COMPOSITION FOR TRANSCOLONIC ABSORPTION

Foreign code F120006994
File No. S2010-1058-C0
Posted date Oct 29, 2012
Country WIPO
International application number 2011JP004642
International publication number WO 2012/023291
Date of international filing Aug 19, 2011
Date of international publication Feb 23, 2012
Priority data
  • P2010-185501 (Aug 20, 2010) JP
Title PHARMACEUTICAL COMPOSITION FOR TRANSCOLONIC ABSORPTION
Abstract

The purpose of the present invention is to provide a pharmaceutical composition for transcolonic absorption which is capable of delivering a biologically active substance (in particular, a water-soluble biologically active substance with a high molecular weight) having sites of action in the cell, not by injection, noninvasively and with high specificity into cells in specific tissues. This pharmaceutical composition for transcolonic absorption is characterized by comprising at least (a) and (b) below: (a) a biologically active substance having sites of action in the cell and to which a lipoprotein introduction substance is bonded, and (b) a compound having a large intestine mucous membrane epithelium permeability enhancing effect for the biologically active substance.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL ANDDENTAL UNIVERSITY,
  • YOKOTA, TAKANORI,
  • MURAKAMI, MASAHIRO,
  • NISHINA, KAZUTAKA
  • Inventor
  • YOKOTA, TAKANORI,
  • MURAKAMI, MASAHIRO,
  • NISHINA, KAZUTAKA
IPC(International Patent Classification)
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