METHOD FOR ASSESSING BREAST CANCER SUSCEPTIBILITY
|Posted date||Jan 11, 2013|
|International application number||2011JP005983|
|International publication number||WO 2012/056694|
|Date of international filing||Oct 26, 2011|
|Date of international publication||May 3, 2012|
|Title||METHOD FOR ASSESSING BREAST CANCER SUSCEPTIBILITY|
The present invention addresses the problem of providing a method for identifying the DNA copy number variation relating to breast cancer susceptibility and assessing breast cancer susceptibility on the basis of an increase or decrease in this DNA copy number variation. The problem is solved by performing microarray analysis using the peripheral blood of a sporadic breast cancer patient, identifying the DNA copy number variation relating to breast cancer susceptibility in a chromosomal region, detecting the number of copies of this DNA copy number variation by quantitative PCR, and thereby assessing breast cancer susceptibility from the increase or decrease in the DNA copy number variation. Furthermore, it is possible to improve the accuracy of the breast cancer susceptibility assessment by detecting the DNA copy number variation using the above-mentioned quantitative PCR in which two or more chromosomal regions have been selected and performing discriminant analysis on the basis of that result.
|IPC(International Patent Classification)||
Contact Information for " METHOD FOR ASSESSING BREAST CANCER SUSCEPTIBILITY "
- YAMAGUCHI UNIVERSITY (In Japanese)学術研究部 産学連携課
- URL: http://www.yamaguchi-u.ac.jp/english/
- Address: (In Japanese)〒755-8611 宇部市常盤台２－１６－１
- Fax: 81-836-85-9962