Top > Search of International Patents > HEPARIN-BINDING PROTEIN HAVING HEPARAN SULFATE SUGAR CHAIN ATTACHED THERETO, PROCESS FOR PRODUCING THE SAME AND MEDICINAL COMPOSITION CONTAINING THE SAME

HEPARIN-BINDING PROTEIN HAVING HEPARAN SULFATE SUGAR CHAIN ATTACHED THERETO, PROCESS FOR PRODUCING THE SAME AND MEDICINAL COMPOSITION CONTAINING THE SAME

Foreign code F130007235
File No. 2005001774
Posted date Mar 27, 2013
Country WIPO
International application number 2005JP006364
International publication number WO 2005/095600
Date of international filing Mar 31, 2005
Date of international publication Oct 13, 2005
Priority data
  • P2004-108570 (Mar 31, 2004) JP
Title HEPARIN-BINDING PROTEIN HAVING HEPARAN SULFATE SUGAR CHAIN ATTACHED THERETO, PROCESS FOR PRODUCING THE SAME AND MEDICINAL COMPOSITION CONTAINING THE SAME
Abstract

A cDNA encoding a peptide capable of having selective heparan sulfate-attachment is bonded to another cDNA encoding a heparin-binding protein and the gene product of this bonded cDNA is produced by animal cells, thereby producing a heparin-binding protein having a heparan sulfate sugar chain attached via a covalent bond in its molecule. Because of having a sulfated glycosaminoglycan sugar chain with little chondroitin sulfate covalently bonded thereto, this heparin-binding protein having a heparan sulfate sugar chain attached thereto has high functions such as being stable to, for example, heat, acids, alkalis and so on in vivo, is effective in cell growth, tissue regeneration and so on, and, moreover, has an effect of controlling the physiological function of FGF. Thus, it is highly useful as a drug for preventing and treating various diseases in which FGF participates.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE,
  • IMAMURA, TORU,
  • ASADA, MASAHIRO,
  • SUZUKI, MASASHI
  • Inventor
  • IMAMURA, TORU,
  • ASADA, MASAHIRO,
  • SUZUKI, MASASHI
IPC(International Patent Classification)
Specified countries AE,AG,AL,AM,AP(GM,KE,LS,MW,MZ,NA,SD,SL,SZ,TZ,UG,ZM,ZW),AT,AU,AZ,BA,BB,BG,BR,BW,BY,BZ,CA,CH,CN,CO,CR,CU,CZ,DE,DK,DM,DZ,EA(AM,AZ,BY,KG,KZ,MD,RU,TJ,TM),EC,EE,EG,EP(AT,BE,BG,CH,CY,CZ,DE,DK,EE,ES,FI,FR,GB,GR,HU,IE,IS,IT,LT,LU,MC,NL,PL,PT,RO,SE,SI,SK,TR),ES,FI,GB,GD,GE,GH,GM,HR,HU,ID,IL,IN,IS,KE,KG,KP,KR,KZ,LC,LK,LR,LS,LT,LU,LV,MA,MD,MG,MK,MN,MW,MX,MZ,NA,NI,NO,NZ,OA(CI,GN,GQ,GW,NE),OM,PG,PH,PL,PT,RO,RU,SC,SD,SE,SG,SK,SL,SM,SY,TJ,TM,TN,TR,TT,TZ,UA,UG,US,UZ,VC,VN,YU,ZA,ZM,ZW

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