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PRODRUG USING NITROIMIDAZOLE meetings

Foreign code F130007249
File No. 12-P17
Posted date Apr 1, 2013
Country WIPO
International application number 2013JP053429
International publication number WO 2013/122112
Date of international filing Feb 13, 2013
Date of international publication Aug 22, 2013
Priority data
  • P2012-028761 (Feb 13, 2012) JP
Title PRODRUG USING NITROIMIDAZOLE meetings
Abstract

Provided is a prodrug of a therapeutically active organic compound having: an amino group, a cyclic amino group or a hydroxyl group in the molecule

and a 2-nitro-1-imidazole propionic acid. In particular, provided is a prodrug in which the therapeutic organic compound is selected from an antitumor agent. Said prodrug specifically cleaves at the low-oxygen site within a living body and exhibits an innate therapeutic activity.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • UNIVERSITY OF TSUKUBA
  • Inventor
  • NAGASAKI, YUKIO,
  • IKEDA, YUTAKA,
  • HISANO, HIKARU
IPC(International Patent Classification)
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