Top > Search of International Patents > 1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME

1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME

Foreign code F130007255
File No. H22-S18
Posted date Apr 2, 2013
Country WIPO
International application number 2012JP062775
International publication number WO 2012/157744
Date of international filing May 18, 2012
Date of international publication Nov 22, 2012
Priority data
  • P2011-111973 (May 19, 2011) JP
  • P2011-247369 (Nov 11, 2011) JP
Title 1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME
Abstract

[Problem] To provide a novel therapeutic agent for solid cancer such as pancreatic cancer. [Solution] A 1-thioxo-1,2,3,4-tetrahydro-ss-carboline derivative represented by general formula [1] wherein R2 represents a hydroxy group, a hydroxyalkylcarbonyl group, a hydroxyaryl group or the like, A represents an alkylene group, and X represents a sulfur atom, which exhibits high cell-killing properties for cancer cells in a highly selective manner and is therefore useful as a therapeutic agent for solid cancer such as pancreatic cancer.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA,
  • KATO ATSUSHI,
  • ADACHI ISAO,
  • TOYOOKA NAOKI,
  • KAJI AKIRA,
  • KURASHIMA YUKIKO,
  • HATA YUKAKO,
  • OGURA TSUTOMU
  • Inventor
  • KATO ATSUSHI,
  • ADACHI ISAO,
  • TOYOOKA NAOKI,
  • KAJI AKIRA,
  • KURASHIMA YUKIKO,
  • HATA YUKAKO,
  • OGURA TSUTOMU
IPC(International Patent Classification)
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