1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME
|Posted date||Apr 2, 2013|
|International application number||2012JP062775|
|International publication number||WO 2012/157744|
|Date of international filing||May 18, 2012|
|Date of international publication||Nov 22, 2012|
|Title||1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME|
[Problem] To provide a novel therapeutic agent for solid cancer such as pancreatic cancer. [Solution] A 1-thioxo-1,2,3,4-tetrahydro-ss-carboline derivative represented by general formula  wherein R2 represents a hydroxy group, a hydroxyalkylcarbonyl group, a hydroxyaryl group or the like, A represents an alkylene group, and X represents a sulfur atom, which exhibits high cell-killing properties for cancer cells in a highly selective manner and is therefore useful as a therapeutic agent for solid cancer such as pancreatic cancer.
|IPC(International Patent Classification)|
Contact Information for " 1-THIOXO-1,2,3,4-TETRAHYDRO-ss-CARBOLINE DERIVATIVE AND ANTI-CANCER AGENT COMPRISING SAME "
- University of TOYAMA Tomidai TLO
- URL: https://sanren.ctg.u-toyama.ac.jp/
- Address: 3190 Gofuku, Toyama-shi, Toyama, Japan , 930-8555
- Phone: 81-76-445-6392
- Fax: 81-76-445-6939