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METHOD FOR DETERMINATION OF PROGNOSIS OF PROSTATE CANCER, AND DIAGNOSTIC AGENT FOR USE IN THE METHOD

Foreign code F130007308
File No. 05-44
Posted date Apr 24, 2013
Country WIPO
International application number 2007JP057048
International publication number WO 2007/119606
Date of international filing Mar 30, 2007
Date of international publication Oct 25, 2007
Priority data
  • P2006-104315 (Apr 5, 2006) JP
Title METHOD FOR DETERMINATION OF PROGNOSIS OF PROSTATE CANCER, AND DIAGNOSTIC AGENT FOR USE IN THE METHOD
Abstract

Disclosed is a method for determination of the possibility of metastasis of prostate cancer. Also disclosed is a diagnostic agent for use in the method. It is found that, in a case where bone metastasis is observed, the probability that the phosphorylation of a threonine residue at position-254 in NF-?B-p65/RelA occurs in a prostate cancer cell is significantly higher than that in a case where bone metastasis is not observed. Therefore, the method for determination of the possibility of metastasis of prostate cancer comprises the step of measuring human NF-?B-p65/RelA having a phosphorylated threonine residue at position-254in a prostate tissue isolated from a human body.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • YOKOHAMA CITY UNIVERSITY,
  • RYO, AKIHIDE,
  • AOKI, ICHIRO,
  • SASAKI, TAKESHI
  • Inventor
  • RYO, AKIHIDE,
  • AOKI, ICHIRO,
  • SASAKI, TAKESHI
IPC(International Patent Classification)
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