COMBINATION MEDICINE FOR TREATMENT OF DEPRESSION
|Posted date||Apr 26, 2013|
|International application number||2012JP001996|
|International publication number||WO 2012/127871|
|Date of international filing||Mar 22, 2012|
|Date of international publication||Sep 27, 2012|
|Title||COMBINATION MEDICINE FOR TREATMENT OF DEPRESSION|
The present invention provides a combination medicine for treatment of depression, comprising a combination of (A1) an antidepressant and either (B1) a dopamine D1 receptor agonist or (C1) a dopamine D1 receptor antagonist
and a method for screening for an antidepressant that in combination with a dopamine D1 receptor agonist provides an improvement in treatment of depression, the method comprising the steps of: administering, to a mammal, (A2) a compound having an antidepressant action and (B1)a dopamine D1 receptor agonist, and detecting a greater increase in depression-related gene expression, dopamine D1 receptor expression and/or dopamine D1 receptor signaling in comparison with the case where (A2) the compound having an antidepressant action or (B1) the dopamine D1 receptor agonist is administered.
|IPC(International Patent Classification)||
Contact Information for " COMBINATION MEDICINE FOR TREATMENT OF DEPRESSION "
- Kurume University Office of Intellectual Property
- URL: http://www.kurume-u.ac.jp/
- Address: 67, Asahi-machi, Kurume-shi, Fukuoka, Japan , 830-0011
- Phone: 81-942-31-7916
- Fax: 81-942-31-7918