IMPROVED OLIGONUCLEOTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID OLIGONUCLEOTIDE
| Foreign code | F130007453 |
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| Posted date | Jul 4, 2013 |
| Country | WIPO |
| International application number | 2012JP064491 |
| International publication number | WO 2012/165653 |
| Date of international filing | May 30, 2012 |
| Date of international publication | Dec 6, 2012 |
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| Title |
IMPROVED OLIGONUCLEOTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID OLIGONUCLEOTIDE
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| Abstract |
The purpose of the present invention is to provide a native linear RNA molecule which can be produced in a simple manner and has nuclease resistance. The present invention provides an RNA molecule which is characterized by comprising a nucleotide sequence represented by general formula (1) or a nucleotide sequence substantially comprising the above-mentioned nucleotide sequence but having the mutation in one to several nucleotides therein, and is also characterized by having nuclease resistance capability. 5'-GGUUAGGGUUACX1X2X3X4X5X6X7X8X9X10X11X12X13X14X15X16ACGAAACAAAAAAUGG-3' (1) [In formula (1), X1 to X16 independently represent any nucleotide selected from adenine, cytosine, guanine and uracil.] |
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Contact Information for " IMPROVED OLIGONUCLEOTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID OLIGONUCLEOTIDE "
- Toyohashi Campus Innovation Co. Section of Technology Transfer
- URL: https://www.tut.ac.jp/cooperation/
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E-mail:
- Address: 1-1, hibarigaoka,tenpakucho,Toyohashi-city,Aichi,Japan , 441-8580
- Fax: 81-532-44-6980
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