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IMPROVED OLIGONUCLEOTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID OLIGONUCLEOTIDE commons meetings

Foreign code F130007453
Posted date Jul 4, 2013
Country WIPO
International application number 2012JP064491
International publication number WO 2012/165653
Date of international filing May 30, 2012
Date of international publication Dec 6, 2012
Priority data
  • P2011-120806 (May 30, 2011) JP
Title IMPROVED OLIGONUCLEOTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAID OLIGONUCLEOTIDE commons meetings
Abstract

The purpose of the present invention is to provide a native linear RNA molecule which can be produced in a simple manner and has nuclease resistance. The present invention provides an RNA molecule which is characterized by comprising a nucleotide sequence represented by general formula (1) or a nucleotide sequence substantially comprising the above-mentioned nucleotide sequence but having the mutation in one to several nucleotides therein, and is also characterized by having nuclease resistance capability. 5'-GGUUAGGGUUACX1X2X3X4X5X6X7X8X9X10X11X12X13X14X15X16ACGAAACAAAAAAUGG-3' (1) [In formula (1), X1 to X16 independently represent any nucleotide selected from adenine, cytosine, guanine and uracil.]

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY,
  • UMEKAGE, SO,
  • OCHI, AKINORI,
  • KIKUCHI, YO
  • Inventor
  • UMEKAGE, SO,
  • OCHI, AKINORI,
  • KIKUCHI, YO
IPC(International Patent Classification)
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