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ANTIBODY AND USE THEREOF 新技術説明会

外国特許コード F130007517
掲載日 2013年7月12日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2012JP070747
国際公開番号 WO 2013024867
国際出願日 平成24年8月15日(2012.8.15)
国際公開日 平成25年2月21日(2013.2.21)
優先権データ
  • 特願2011-179161 (2011.8.18) JP
発明の名称 (英語) ANTIBODY AND USE THEREOF 新技術説明会
発明の概要(英語) Provided is a means whereby active reelin can be selectively measured in a simple and rapid fashion, even in high-volume samples. An anti-active reelin antibody that binds specifically to active reelin but does not bind to inactive reelin; alternatively, an anti-active reelin antibody that binds specifically to a peptide having the amino acid sequence shown by SEQ ID NO: 1 in the sequence listing.
従来技術、競合技術の概要(英語) BACKGROUND ART
And the phosphorus Lee, is critical to the function of the brain, more than 3400 amino acids large secreted proteins. Characteristic of the brain Lee phosphorus to be essential for the formation of the layer structure, whether human or phosphorus lost Lee hypoplasia may occur such as brain structures have been reported. On the other hand, phosphorus is also expressed in adult brain Lee and, decrease in the amount of its expression enhancement or decomposition in schizophrenia, Alzheimer's disease, mood disorders contribute to diseases such as have been revealed. With respect to the phosphorus Lee, in for example Japanese Patent Application Laid-phosphorus Lee 1 epitope regions and encoding polynucleotide of the polypeptide and, thereby to further study the function of phosphorus and Lee, as well as the arrangement of the phosphorus gene Lee neurons caused by malfunction of the abnormality diagnosis for brain disorders, can be provided with treatment means. Also, in the following Patent Literature 2, a significant component in the other of the central nervous system to non-destructively assess or predict DIIA level as a biomarker for a method of measuring the leakage rate of phosphorus is proposed.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • Public University Corporation Nagoya City University
  • 発明者(英語)
  • HATTORI Mitsuharu
  • KOHNO Takao
  • KOIE Mari
  • HISANAGA Arisa
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IS JP KE KG KM KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PE PG PH PL PT QA RO RS RU RW SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG
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