PLANAR PATCH CLAMP DEVICE, ELECTRODES FOR SAID DEVICE AND CELL ION CHANNEL CURRENT MEASUREMENT METHOD
In order to reduce a noise current by suppressing variations in an applied membrane potential in a planar patch clamp device, enabling an ion channel current to be accurately measured, this planar patch clamp device is provided with a liquid reservoir that has at least one fine through-hole disposed on an electrically insulative substrate, and holds a conductive liquid on surfaces on both sides of the through-hole
and electrodes, which are capable of being energized, are disposed in said liquid reservoir. The electrodes are provided with: (a) an electrode vessel, wherein part of the vessel wall comprises an inorganic porous material
(b) an electrode, wherein a noble metal chloride (NmCl) layer is formed on the surface of the noble metal (Nm)
and (c) an electrode solution, wherein the noble metal chloride and an alkali metal chloride are dissolved at a saturated concentration.