METHOD FOR PRODUCING MODEL ANIMAL, AND MODEL ANIMAL
外国特許コード | F130007582 |
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整理番号 | S2011-0908-C0 |
掲載日 | 2013年7月24日 |
出願国 | 世界知的所有権機関(WIPO) |
国際出願番号 | 2012JP065668 |
国際公開番号 | WO 2013/094240 |
国際出願日 | 平成24年6月19日(2012.6.19) |
国際公開日 | 平成25年6月27日(2013.6.27) |
優先権データ |
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発明の名称 (英語) | METHOD FOR PRODUCING MODEL ANIMAL, AND MODEL ANIMAL |
発明の概要(英語) |
Provided are: a method for producing a model animal which has a desired lifetime, and in which a predetermined biological reaction can be induced and a model animal. According to the present invention, a first individual in which a gene of interest is heterozygously deficient is produced using a first ES cell originated from a non-human mammal. On the other hand, a fragment containing a homologous gene that has homology with the gene of interest is produced. Using a second ES cell that is so adapted that a predetermined region on X-chromosome of the mammal can be substituted, the fragment is introduced into the second ES cell, thereby producing a substituted ES cell in which the predetermined region is substituted by the fragment. Using the substituted ES cell, a second individual is produced. The first individual and the second individual are mated with each other, thereby producing a model animal. |
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国際特許分類(IPC) |
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日本語項目の表示
発明の名称 | モデル動物の作出方法及びモデル動物 |
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『 METHOD FOR PRODUCING MODEL ANIMAL, AND MODEL ANIMAL 』に関するお問合せ
- 国立大学法人 熊本大学 マーケティング推進部 産学連携ユニット
- URL: https://www.kumamoto-u.ac.jp/kenkyuu_sangakurenkei
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E-mail:
- Address: 〒860-8555 熊本県熊本市黒髪2-39-1
- TEL: 096-342-3277
- FAX: 096-342-3239