NOVEL ANTI-MALIGNANT TUMOR AGENT
|Posted date||Aug 16, 2013|
|International application number||2013JP051275|
|International publication number||WO 2013/111770|
|Date of international filing||Jan 23, 2013|
|Date of international publication||Aug 1, 2013|
|Title||NOVEL ANTI-MALIGNANT TUMOR AGENT|
The present invention provides an anti-tumor agent which is a molecular targeted drug for a malignant tumor and is highly safe. An anti-malignant tumor agent characterized by comprising, as an active ingredient, a substance capable of targeting a ribosome protein of which the expression is increased in a malignant tumor cell. The substance capable of targeting a ribosome protein of which the expression is increased in a malignant tumor cell according to the present invention is considered as a substance involved in a biological defense mechanism that is believed to be provided intrinsically in a living body and can prevent the development of diseases even if a cancer cell is generated. Specifically, the ribosome protein of which the expression is increased is RPL29 and/or RPS4X. A substance capable of targeting RPL29 and/or RPS4X is an anti-RPL29 antibody and/or an anti-RPS4X antibody, a substance capable of activating or enhancing an endogenous anti-RPL29 antibody and/or an endogenous anti-RPS4X antibody occurring in a living body, a substance capable of inducing the production of an anti-RPL29 antibody and/or an anti-RPS4X antibody in a living body, or an antagonist of RPL29 and/or RPS4X. The present invention also provides a method for testing an malignant tumor, in which an anti-RPL29 antibody titer and/or an anti-RPS4X antibody titer is employed as a measure.
|IPC(International Patent Classification)||
Contact Information for " NOVEL ANTI-MALIGNANT TUMOR AGENT "
- Okayama University Intellectual Property Office
- URL: http://www.okayama-u.ac.jp/user/orpc-ehp/index/index.html
- Address: 1-1-1 Tsushima-naka , Kita-ku , Okayama-city, Japan , 700-8530
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