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FLUORESCENT SENSOR FOR PHOSPHATE ION AND PHOSPHORYLATED PEPTIDE

Foreign code F040000762
File No. (K012P10)
Posted date Feb 22, 2005
Country WIPO
International application number 2003JP000705
International publication number WO 2003071280
Date of international filing Jan 27, 2003
Date of international publication Aug 28, 2003
Priority data
  • P2002-045846 (Feb 22, 2002) JP
Title FLUORESCENT SENSOR FOR PHOSPHATE ION AND PHOSPHORYLATED PEPTIDE
Abstract A fluorescent sensor for phosphate ions or phosphorylated peptides which comprises a compound selectively fluorescing by the action of phosphate ions and represented by the following general formula (1). In the formula (1), FL represents a fluorescent functional group or fluorescent group of atoms which has an aromatic ring or heterocycle (e.g., dimethylanthryl) and X represents a functional group or group of atoms which undergoes elimination in an aqueous solution to become an anion (e.g., NO3).
Scope of claims (In Japanese)1. 下記の一般式(1)で表わされるリン酸アニオン選択的発蛍光性化合物から成ることを特徴とするリン酸イオンおよびリン酸化ペプチド用蛍光センサー。〔式(1)中、FLは、芳香環または複素環を有する発蛍光性官能基または原子団を表わし、Xは、水溶液中で脱離してアニオンと成る官能基または原子団を表わす。〕
2. FLが、下記の(2)に示す(a)、(b)、(C)または(d)の1つから選ばれることを特徴とする請求項1の発蛍光性化合物。〔式(d)において、Rは、水素原子、炭素数1~4のアルキル基、またはベンジル基を表わす。〕
3. Xが、NO3、ハロゲン原子、またはC104であることを特徴とする請求項1または2の発蛍光性化合物。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • Inventor
  • HAMACHI, Itaru
IPC(International Patent Classification)
Specified countries National States: US
EPO: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR
Reference ( R and D project ) PRESTO Organization and Function AREA
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