CANCER MALIGNANCY TESTING METHOD, PLURIPOTENT TUMORIGENIC CELLS, AND PREPARATION METHOD THEREFOR
The present invention provides: a method for testing the latent malignancy of a cell population
new tumorigenic cells that are useful for discovering the mechanisms associated with cancer and developing cancer therapy
and a method for preparing said cells. The present invention is characterized by the creation of pluripotent tumorigenic cells from non-tumorigenic cells via hypoxia-induced reprogramming, and/or by the use of SSEA-1, SSEA-3, TRA-1-60 or TRA-1-81 as a specific cell surface marker associated with the pluripotent tumorigenic cells.