Top > Search of International Patents > CANCER MALIGNANCY TESTING METHOD, PLURIPOTENT TUMORIGENIC CELLS, AND PREPARATION METHOD THEREFOR

CANCER MALIGNANCY TESTING METHOD, PLURIPOTENT TUMORIGENIC CELLS, AND PREPARATION METHOD THEREFOR

Foreign code F130007658
File No. S2012-0542-N0
Posted date Oct 17, 2013
Country WIPO
International application number 2013JP055865
International publication number WO 2013/133220
Date of international filing Mar 4, 2013
Date of international publication Sep 12, 2013
Priority data
  • P2012-052348 (Mar 8, 2012) JP
Title CANCER MALIGNANCY TESTING METHOD, PLURIPOTENT TUMORIGENIC CELLS, AND PREPARATION METHOD THEREFOR
Abstract

The present invention provides: a method for testing the latent malignancy of a cell population

new tumorigenic cells that are useful for discovering the mechanisms associated with cancer and developing cancer therapy

and a method for preparing said cells. The present invention is characterized by the creation of pluripotent tumorigenic cells from non-tumorigenic cells via hypoxia-induced reprogramming, and/or by the use of SSEA-1, SSEA-3, TRA-1-60 or TRA-1-81 as a specific cell surface marker associated with the pluripotent tumorigenic cells.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, JAPAN
  • Inventor
  • UENO, HIKARU,
  • SUZUKI, MITSUHIRO
IPC(International Patent Classification)

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