FLUORINE-CONTAINING Alpha,Beta-UNSATURATED ALDEHYDE, METHOD FOR PRODUCING SAME, OPTICALLY ACTIVE FLUORINE-CONTAINING COMPOUND USING FLUORINE-CONTAINING Alpha,Beta-UNSATURATED ALDEHYDE, AND METHOD FOR PRODUCING SAME

• 特願2012-052188 (2012.3.8) JP

The purpose of the present invention is to provide a fluorine-containing alpha,beta-unsaturated aldehyde, a method for producing same, an optically active fluorine-containing compound using the fluorine-containing alpha,beta-unsaturated aldehyde, and a method for producing same. This method for producing a fluorine-containing alpha,beta-unsaturated aldehyde is a method for producing a fluorine-containing alpha,beta-unsaturated aldehyde represented by formula (1) and comprises: an oxidizing step of oxidizing an alcohol represented by formula (2) in a high-boiling-point solvent, which has a higher boiling point than the corresponding alpha,beta-unsaturated aldehyde, by using an oxidizing agent that is insoluble to the high-boiling-point solvent

and a purifying step of purifying the reaction solution obtained in the oxidizing step by distillation. In formulae (1) and (2), R1 and R2 each independently represent a hydrogen atom or a fluorine atom, and X is 2 or 3.

• TOYOHASHI UNIVERSITY OF TECHNOLOGY

• SHIBATOMI KAZUTAKA

• C07C  45/29      水酸基の
• B01J  23/44      パラジウム
• B01J  31/02      有機化合物または金属水素化物を含有するもの
• C07B  53/00      不整合成
• C07C  47/24      ハロゲンを含むもの
• C07C 249/04      オキシムの
• C07C 251/56      炭化水素基が二重結合の酸素原子で置換されているもの
• C07C 319/18      不飽和化合物にチオールを付加させることによるもの
• C07C 323/22      チオ基と同じ炭素骨格に結合している二重結合の酸素原子を含有するもの