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METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY

Foreign code F130007693
File No. S2012-0506-N0
Posted date Nov 1, 2013
Country WIPO
International application number 2013JP002361
International publication number WO 2013/157215
Date of international filing Apr 5, 2013
Date of international publication Oct 24, 2013
Priority data
  • P2012-094198 (Apr 17, 2012) JP
Title METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY
Abstract

The present invention addresses the problem of providing a method for identifying a human chromosomal region comprising a base sequence with approximately 100 b, said chromosomal region showing a DNA copy number variation relating to sensitivity to endometrial cancer, and assessing endometrial cancer susceptibility on the basis of an increase or decrease in this DNA copy number variation. According to this method, endometrial cancer susceptibility can be assessed by: first, isolating a chromosomal region that shows a DNA copy number variation characteristic to endometrial cancer, by screening with the use of a microarray derived from peripheral blood

then, identifying DNA in a human chromosomal region comprising a base sequence represented by any of SEQ ID NOS:1-7 relating to sensitivity to endometrial cancer, said chromosomal region being selected from among not only the chromosomal region isolated by the aforesaid screening but also a great number of chromosomal regions including chromosomal regions that are not covered by the microarray

and then detecting a decrease in the DNA copy number in the human chromosomal region comprising the base sequence represented by any of SEQ ID NOS:1-7.

  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • YAMAGUCHI UNIVERSITY
  • Inventor
  • SUEHIRO, YUTAKA,
  • SASAKI, KOHSUKE,
  • OKADA, TAKAE
IPC(International Patent Classification)

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