METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY
|Posted date||Nov 1, 2013|
|International application number||2013JP002361|
|International publication number||WO 2013/157215|
|Date of international filing||Apr 5, 2013|
|Date of international publication||Oct 24, 2013|
|Title||METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY|
The present invention addresses the problem of providing a method for identifying a human chromosomal region comprising a base sequence with approximately 100 b, said chromosomal region showing a DNA copy number variation relating to sensitivity to endometrial cancer, and assessing endometrial cancer susceptibility on the basis of an increase or decrease in this DNA copy number variation. According to this method, endometrial cancer susceptibility can be assessed by: first, isolating a chromosomal region that shows a DNA copy number variation characteristic to endometrial cancer, by screening with the use of a microarray derived from peripheral blood
then, identifying DNA in a human chromosomal region comprising a base sequence represented by any of SEQ ID NOS:1-7 relating to sensitivity to endometrial cancer, said chromosomal region being selected from among not only the chromosomal region isolated by the aforesaid screening but also a great number of chromosomal regions including chromosomal regions that are not covered by the microarray
and then detecting a decrease in the DNA copy number in the human chromosomal region comprising the base sequence represented by any of SEQ ID NOS:1-7.
|IPC(International Patent Classification)|
Contact Information for " METHOD FOR ASSESSING ENDOMETRIAL CANCER SUSCEPTIBILITY "
- YAMAGUCHI UNIVERSITY (In Japanese)学術研究部 産学連携課
- URL: http://www.yamaguchi-u.ac.jp/english/
- Address: (In Japanese)〒755-8611 宇部市常盤台２－１６－１
- Fax: 81-836-85-9962