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Microdroplet-producing apparatus

Foreign code F140007863
File No. 09T275P/US
Posted date Apr 24, 2014
Country United States of America
Application number 201113261564
Gazette No. 20130129581
Gazette No. 9200938
Date of filing Jul 13, 2011
Gazette Date May 23, 2013
Gazette Date Dec 1, 2015
International application number JP2011066004
International publication number WO2012008497
Date of international filing Jul 13, 2011
Date of international publication Jan 19, 2012
Priority data
  • P2010-158988 (Jul 13, 2010) JP
  • 2011WO-JP66004 (Jul 13, 2011) WO
Title Microdroplet-producing apparatus
Abstract (US9200938)
The present invention provides an apparatus for producing micro liquid drops through fine channels which can produce a large amount of micro liquid drops at low costs in an efficient manner.
The apparatus for producing micro liquid drops according to the present invention includes a fine channel substrate and a holder for holding the fine channel substrate.
The fine channel substrate has a micro liquid drop discharge outlet formed at the center thereof; a plurality of micro liquid drop producing sections which are connected to the micro liquid drop discharge outlet via the fine channels and disposed on the respective circumference of M circles or polygons arranged around the micro liquid drop discharge outlet; first-liquid drawing inlets which are disposed on the circumference of a circle or polygon arranged around the micro liquid drop discharge outlet; up-to-Nth-liquid drawing inlets (N is an integer equal to two or greater, M≰N-1) which are disposed on the respective circumference of circles or polygons arranged sequentially outward; and the fine channels through which the first- to Nth-liquids are supplied to the plurality of micro liquid drop producing sections.
The holder for holding the fine channel substrate has a multi-pipe structure which includes N annular channels for distributing an equal flow of the first- to Nth-liquids to the drawing inlet for each liquid in the fine channel substrate.
Scope of claims [claim1]
1. An apparatus for producing microdroplets using microchannels, said apparatus comprising a microchannel board and a holder for retaining the microchannel board, wherein
the microchannel board has a microdroplet-outlet port formed at the center thereof, microdroplet-forming parts on a first to a Mth (M is an integer of 1 or more) annular or polygonal peripheries from inside to outside, said parts being connected through the microchannels to the microdroplet-outlet port and a plurality of said parts being disposed on each of M annular or polygonal peripheries with the microdroplet-outlet port at the center, inlet ports for a first liquid disposed on annular or polygonal peripheries with the microdroplet-outlet port at the center, inlet ports for liquids up to a Nth liquid (N is an integer of 2 or more, M <= N-1) sequentially disposed on annular or polygonal peripheries further outside of the above peripheries, and microchannels for feeding the first to the Nth liquids to the above plurality of microdroplet-forming parts, and
the holder for retaining the microchannel board has a coaxial multitube structure, with the microdroplet-outlet port as the central axis, having N annular or polygonal annular channels for allocating the even flow rate of the above first to the Nth liquids to the inlet port for each liquid of the microchannel board, wherein
N=2 (simultaneously M=1), the first liquid is a dispersion phase, and the second liquid is a continuous phase, and
the holder for retaining the microchannel structure has a third component which is disposed under the microchannel board and which is equipped with an inlet port for the continuous phase, a second component which is equipped with an inlet port for the dispersion phase and which forms annular or polygonal annular channels for feeding the continuous phase to the microchannel board in combination with the above third component, and a first component which forms a annular path for feeding the dispersion phase to the microchannel board in combination with the above second component and which is equipped, at the center thereof, with a cylinder having an outlet port for microdroplets from the microchannel board, wherein the first and second components are placed beneath the third component, and the first component is placed beneath the second component.
[claim2]
2. The apparatus for producing microdroplets according to claim 1, wherein the plurality of microdroplet-forming parts are where the dispersion phase liquid alternately joins with the continuous phase liquid from both sides.
[claim3]
3. An apparatus for producing microdroplets using microchannels, said apparatus comprising a microchannel board and a holder for retaining the microchannel board, wherein
the microchannel board has a microdroplet-outlet port formed at the center thereof, microdroplet-forming parts on a first to a Mth (M is an integer of 1 or more) annular or polygonal peripheries from inside to outside, said parts being connected through the microchannels to the microdroplet-outlet port and a plurality of said parts being disposed on each of M annular or polygonal peripheries with the microdroplet-outlet port at the center, inlet ports for a first liquid disposed on annular or polygonal peripheries with the microdroplet-outlet port at the center, inlet ports for liquids up to a Nth liquid (N is an integer of 2 or more, M <= N-1) sequentially disposed on annular or polygonal peripheries further outside of the above peripheries, and microchannels for feeding the first to the Nth liquids to the above plurality of microdroplet-forming parts, and
the holder for retaining the microchannel board has a coaxial multitube structure, with the microdroplet-outlet port as the central axis, having N annular or polygonal annular channels for allocating the even flow rate of the above first to the Nth liquids to the inlet port for each liquid of the microchannel board, wherein
N=2 (simultaneously M=1), the first liquid is a continuous phase, and the second liquid is a dispersion phase, and
the holder for retaining the microchannel structure has a third component which is disposed under the microchannel board and which is equipped with an inlet port for the dispersion phase, a second component which is equipped with an inlet port for the continuous phase and which forms annular or polygonal annular channels for feeding the continuous phase to the microchannel board in combination with the above third component, and a first component which is equipped with an outlet port for the formed droplets from the holder and which forms a annular or polygonal annular channel for feeding the continuous phase to the microchannel board in combination with the above second component and which is equipped, at the center thereof, with a cylinder having an outlet port for microdroplets from the microchannel board, wherein the first and second components are placed beneath the third component, and the first component is placed beneath the second component.
[claim4]
4. The apparatus for producing microdroplets according to claim 3, wherein the plurality of microdroplet-forming parts are where the continuous phase joins with the above dispersion phase from both sides.
  • Inventor, and Inventor/Applicant
  • NISISAKO TAKASI
  • TOKYO INSTITUTE OF TECHNOLOGY
IPC(International Patent Classification)

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