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OPHTHALMIC COMPOSITION

Foreign code F150008224
Posted date Mar 26, 2015
Country WIPO
International application number 2014JP059838
International publication number WO 2014163142
Date of international filing Apr 3, 2014
Date of international publication Oct 9, 2014
Priority data
  • P2013-077862 (Apr 3, 2013) JP
Title OPHTHALMIC COMPOSITION
Abstract The present invention addresses the problem of providing an ophthalmic composition that holds promise for having a long-lasting effect and therapeutic effect on serious cases and is efficacious in treating dry eye. The ophthalmic composition comprises as an active ingredient a compound having a moisture adjusting effect in a digestive tract. A preferable example of the compound having a moisture adjusting effect in a digestive tract is a member selected from among bisacodyl, picosulfate and pharmaceutically acceptable salts thereof. The active ingredient of the ophthalmic composition according to the present invention can increase tear volume in an eye to be treated. When bisacodyl or picosulfate is used as the active ingredient of the ophthalmic composition according to the present invention, an increase in tear volume can be observed several minutes to several hours, for example 3 hours, after instillation.
Scope of claims (In Japanese)[請求項1]
消化管において水分調整作用を有する化合物を有効成分として含む、眼科用組成物。
[請求項2]
涙量に関連した疾患または状態を処置するための、請求項1に記載の眼科用組成物。
[請求項3]
涙量に関連した疾患または状態が、ドライアイである、請求項2に記載の眼科用組成物。
[請求項4]
点眼液である、請求項1~3のいずれか1項に記載の眼科用組成物。
[請求項5]
消化管において水分調整作用を有する化合物が、ビサコジル、ピコスルファートおよび製薬上許容されるその塩から選択されるいずれかである、請求項1~4のいずれか1項に記載の眼科用組成物。
[請求項6]
有効成分を0.05~3%含有する、請求項1~5のいずれか1項に記載の眼科用組成物。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • EHIME UNIVERSITY
  • Inventor
  • OHASHI YUICHI
  • SHIRAISHI ATSUSHI
  • KOBAYASHI TAKESHI
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN TD TG
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