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METHOD FOR DETERMINING PROGNOSIS OF CANCER

外国特許コード F150008455
整理番号 4130
掲載日 2015年10月21日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2014JP063527
国際公開番号 WO 2014185550
国際出願日 平成26年5月15日(2014.5.15)
国際公開日 平成26年11月20日(2014.11.20)
優先権データ
  • 特願2013-104027 (2013.5.16) JP
発明の名称 (英語) METHOD FOR DETERMINING PROGNOSIS OF CANCER
発明の概要(英語) The present invention relates to a method for determining prognosis of cancer in a subject, which comprises the step of detecting phosphorylation of a tyrosine residue at position 2681 of TRIO in a sample obtained from the subject.
従来技術、競合技術の概要(英語) BACKGROUND ART
Cancer is the leading cause of death in most industrialized nations, and the direct cause of cancer death is often its metastasis to the vital organs. Colorectal cancer is the third most common cause of cancer mortality in Japan. Every year, -100 new patients of colorectal cancer are diagnosed per population of 100,000, and the mortality rate is 30-40 per 100,000 patients ; and it is still increasing.
Cancer treatment, such as chemotherapy and radiation has associated risks, and it is important to optimally select patients most likely to benefit. Although there are several studies on prognostic markers for colorectal cancer (Non-patent literatures 1-7) , they are not enough to identify patients with good prognoses for whom risky therapy would not be necessary. CITATION LIST
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KYOTO UNIVERSITY
  • 発明者(英語)
  • TAKETO, Makoto
  • SONOSHITA, Masahiro
  • SAKAI, Yoshiharu
  • KAWADA, Kenji
  • ITATANI, Yoshiro
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LT LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN TD TG
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