TOP > 外国特許検索 > HOST REGULATION FACTOR FOR ENHANCING PROLIFERATION AND PROPAGATION OF VACCINIA VIRUS

HOST REGULATION FACTOR FOR ENHANCING PROLIFERATION AND PROPAGATION OF VACCINIA VIRUS

外国特許コード F170009025
整理番号 (S2015-1760-N0)
掲載日 2017年3月29日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP071538
国際公開番号 WO 2017014296
国際出願日 平成28年7月22日(2016.7.22)
国際公開日 平成29年1月26日(2017.1.26)
優先権データ
  • 特願2015-145153 (2015.7.22) JP
発明の名称 (英語) HOST REGULATION FACTOR FOR ENHANCING PROLIFERATION AND PROPAGATION OF VACCINIA VIRUS
発明の概要(英語) The objective of the present invention is to provide a use for a UCA1 gene, which is a host regulation factor that enhances proliferation and propagation of the vaccinia virus, so that cancer virotherapy using the vaccinia virus can be effectively carried out. The present invention is: a method for making a predictive evaluation of the efficacy of a cancer treatment using the vaccinia virus, by measuring the expression of the UCA1 gene in cancer cells of a cancer patient, and if the UCA1 gene is expressed, predicting that a cancer treatment using the vaccinia virus will be effective in the patient; and a vaccinia virus introduced in a manner enabling UCA1 gene expression.
従来技術、競合技術の概要(英語) BACKGROUND ART
In recent years, the treatment of cancer virus viral treatment of cancer in a variety of techniques have been developed. Such as used in the treatment of virus, adenovirus, retrovirus other, is vaccinia virus.
Vaccinia virus in recent years, its wide host range and high expression efficiency characteristics, the foreign gene has been introduced as an expression vector for infection (HIV and SARS) have also been used as a multivalent vaccine.
In addition, the solubility of vaccinia virus using cancer cells, the technique used for the treatment of cancer have been reported (see patent document 1 and patent document 2).
In embryo development and tumor formation as the genes responsible for the UCA1 have been reported (non-patent document 1 - see non-patent document 4). UCA1(Urothelial cancer associated 1) gene, encodes a protein that is not a long-chain noncoding RNA(long-non coding RNA: lncRNA) and, used as a marker of bladder cancer and the like have been reported.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY
  • 発明者(英語)
  • NAKAMURA Takafumi
  • HORITA Kousuke
  • KUROSAKI Hajime
  • NAKATAKE Motomu
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
ライセンスをご希望の方、特許の内容に興味を持たれた方は、下記「問合せ先」まで直接お問い合わせください。

PAGE TOP

close
close
close
close
close
close