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SPECTROSCOPE

Foreign code F170009030
File No. (S2015-1758-N0)
Posted date Apr 11, 2017
Country WIPO
International application number 2016JP070287
International publication number WO 2017007024
Date of international filing Jul 8, 2016
Date of international publication Jan 12, 2017
Priority data
  • P2015-137321 (Jul 8, 2015) JP
Title SPECTROSCOPE
Abstract This spectroscope (1) is composed of a conjugate-plane-imaging optical system and a one-shot optical system. In a conjugate-plane-imaging optical system, the image of an object (object surface) to be measured forms an optically conjugate plane with an object surface using an imaging lens or wide-angle lens, and a micro objective lens or other lens (11) that corresponds to a magnification and a visual range which are observation conditions. The conjugate plane is the object surface of a one-shot optical system, and a multiple slit (13) is disposed in the conjugate plane. The multiple slit (13) has a plurality of apertures arranged in periodic fashion in a predetermined direction. The one-shot optical system is an infinity-corrected imaging optical system brought about by an objective lens (15) and an imaging lens (17), and has a phase shifter (19) disposed in the vicinity of a Fourier transform plane, a 2D light-receiving array device (21) disposed in the imaging plane of the imaging lens (17), and a plano-concave cylindrical lens (23) disposed between the multiple slits (13) and the objective lens (15).
Outline of related art and contending technology BACKGROUND ART
Cholesterol contained in blood glucose the amount of biological components such as diabetes and hyperlipidemia and the like, can be indicative of various diseases, for the prophylaxis and treatment of diseases in the prior art in the blood of the amount of biological components of the management is carried out. To measure the amount of biological components of blood is, usually, the use of the collected blood from the body, the collection of blood is painful. In addition, the disinfection of the blood collection site of the consumables or blood is used as the need for a troublesome operation for processing and the like, for the purpose of preventing disease for measuring the amount of biological components of blood are routinely carried out is avoided.
Therefore, blood is taken to measure the amount of the biological components without a non-invasive measurement method (Patent Document 1) have been proposed. In this method, the test site of a living body is irradiated with light, whereby the site of the subject in the interior of the light emitted from a biological component (object light) from the spectral characteristic of the biological component is a qualitative, quantitative measurement. Specifically, the biological component is configured to optically transparent and diffusing the light emitted from the light-emitting areas, such as scattered light as object light, a phase shifter via the objective lens and the movable mirror unit is guided to the fixed mirror, two mirrors 2 are reflected from the object light beam is converged by the imaging optical system, in the imaging plane of the interference. The movable mirror is moved by the piezoelectric element and as a result, the amount of movement of the movable mirror portion of the phase difference corresponding to the object light beam reflected in the fixed mirror and the movable mirror generated in the light fluxes reflected from the object, both light beams with which the intensity of the interference light due to the change, to form a so-called interferogram. The interferogram by Fourier-transforming the spectral characteristics of the object light (spectrum) are obtained.
However, in the above-described measurement method, a light intensity distribution of interference in the imaging plane of the region to be examined by a texture (surface status) the diffraction angle being affected. That is, the refractive index distribution of the object to be examined and the like where the light passes through the optical texture of the difference in light quantity distribution of the object in the image plane are different from each other, the light amount distribution, the interference depends on the concentration of a biological component to be superimposed on the amount of light distribution and thus, the concentration of the biological component may not be accurately measured.
In addition, in the case of a spatially coherent light, the texture is almost no higher order diffracted light from the specimen are generated, only the 0 order light. Koehler illumination is irradiated onto the sample for example, primary light 0 from the sample reaches the objective lens as a parallel light beam, optical Fourier conversion surface of the light is condensed. In such a case the object cannot be divided, it is not possible to obtain the spectral characteristics.
On the other hand, in Patent Document 2, a conjugate image of the object surface once an imaging optical system, optically conjugate with the object plane is formed on the lens surface, the conjugate on the image plane of the object type diffraction grating disposed on the light beam is applied to the spatial period change disclosed technique. Is applied to the spatial period change of the object light beam is guided to the phase shifter via the objective lens. According to this method, there is almost no texture or light from the sample is a clear interferogram can be acquired, the spectral characteristics of light can be obtained (Patent Document 2, see Non-Patent Document 1). Type diffraction grating is, focusing to the optical axis direction (the direction of the imaged line) are alternately arranged in a light-transmitting portion of the present invention, the interval (period) of a translucent portion of the collecting unit or the light-transmitting axis direction and the interference in the optical axis direction (focusing direction perpendicular to the optical axis direction) of the length (length and width of the light transmitting portion) is several tens to several hundred µm µm - very small, also referred to as a multiple slit.
Scope of claims (In Japanese)[請求項1]
a) 被測定物の測定領域内に位置する複数の測定点からそれぞれ発せられた測定光を所定の第1軸方向に2つに分割して第1測定光及び第2測定光を形成する分割光学系と、
b) 前記第1測定光及び前記第2測定光の間に、前記第1軸方向と直交する方向である第2軸方向に沿って連続的に変化する光路長差を付与する光路長差付与手段と、
c) 連続的に変化する光路長差が付与された前記第1測定光及び前記第2測定光を前記第1軸方向に集光させて結像面上に直線状の干渉光を形成する結像光学系と、
d) 前記結像面上に前記第2軸方向に所定の周期で配置された複数の画素を有する、前記干渉光の強度を検出する干渉光検出部と、
e) 前記干渉光検出部で検出された前記干渉光の光強度に基づき、前記被測定物の測定点のインターフェログラムを求め、このインターフェログラムをフーリエ変換することによりスペクトルを取得する処理部と、
f) 前記被測定物と前記分割光学系の間に配置された、該分割光学系と共通の共役面を有するとともに、該共役面に前記測定点からの測定光を結像する共役面結像光学系と、
g) 前記共役面に配置された、前記第1軸方向に周期的に並ぶ透光部と遮光部とを有する振幅型回折格子と、
h) 前記測定光が前記振幅型回折格子を通過した後の光を前記第2軸方向に拡散させる拡散光学系と
を備えることを特徴とする分光測定装置。
[請求項2]
前記拡散光学系が、平凹面シリンドリカルレンズから構成されていることを特徴とする請求項1に記載の分光測定装置。
[請求項3]
前記拡散光学系が、1組の凸面シリンドリカルレンズから構成されていることを特徴とする請求項1に記載の分光測定装置。
[請求項4]
a) 被測定物の測定領域内に位置する複数の測定点からそれぞれ発せられた測定光を所定の第1軸方向に2つに分割して第1測定光及び第2測定光を形成する分割光学系と、
b) 前記第1測定光及び前記第2測定光の間に、前記第1軸方向と直交する方向である第2軸方向に沿って連続的に変化する光路長差を付与する光路長差付与手段と、
c) 連続的に変化する光路長差が付与された前記第1測定光及び前記第2測定光を前記第1軸方向に集光させて結像面上に直線状の干渉光を形成する結像光学系と、
d) 前記結像面上に前記第2軸方向に所定の周期で配置された複数の画素を有する、前記干渉光の強度を検出する干渉光検出部と、
e) 前記干渉光検出部で検出された前記干渉光の光強度に基づき、前記被測定物の測定点のインターフェログラムを求め、このインターフェログラムをフーリエ変換することによりスペクトルを取得する処理部と、
f) 前記被測定物と前記分割光学系の間に配置された、該分割光学系と共通の共役面を有するとともに、該共役面に前記測定点からの測定光を結像する共役面結像光学系と、
g) 前記共役面に配置された、前記第1軸方向に周期的に並ぶ透光部と遮光部とを有する振幅型回折格子とを備え、
前記干渉光検出器が、前記第2軸方向に所定の周期で配置されたm個の画素からなる画素列を第1軸方向にn個並べたm×n個の画素を備え、各画素列を構成する画素の位置が、隣接する画素列を構成する画素の位置とずれるように互い違いに配置されており、
前記結像光学系が、第1測定光と第2測定光の干渉光を、前記干渉光検出器の複数の画素列に跨るように形成することを特徴とする分光測定装置。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY
  • Inventor
  • ISHIMARU, Ichiro
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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