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CANCER INVASION DEPTH DIAGNOSIS SYSTEM

Foreign code F170009031
File No. (S2015-0951-N0)
Posted date Apr 11, 2017
Country WIPO
International application number 2016JP070460
International publication number WO 2017010461
Date of international filing Jul 11, 2016
Date of international publication Jan 19, 2017
Priority data
  • P2015-139114 (Jul 10, 2015) JP
Title CANCER INVASION DEPTH DIAGNOSIS SYSTEM
Abstract A cancer invasion depth diagnosis system is provided with an endoscope, a micro-tomographic probe for acquiring an optical interference signal by emitting low-coherence light onto a tissue of interest where a tumor of interest is located, the micro-tomographic probe being inserted into the body together with the endoscope, and a determination unit for acquiring a tomographic image of the tissue of interest including the tumor of interest and blood flow velocity information in the blood vessels within the tomographic image, on the basis of the optical interference signal. The determination unit determines the invasion depth of the tumor of interest on the basis of the tomographic image and blood flow velocity information.
Outline of related art and contending technology BACKGROUND ART
Generated in the gastrointestinal tract cancer, early stage cancer may be less risk of metastases in the art will appreciate, some of which are capable of ablation of the endoscope. On the other hand, when the advanced cancer, and increases the risk of metastases, basically a surgical resection. Therefore, the gastrointestinal tract in order to properly treat a cancer, early cancer or cancer progression can be important to determine accurately, so that the depth of tumor invasion (degree of the increase in the thickness direction of the tissue) to correctly evaluate becomes a key.
Gastrointestinal tract to evaluate the degree of reaching depth of the cancer, NBI (Narrow-Band Imaging) method using the image obtained by the method has been known (see for example Patent Document 1). In this method, NBI method the acquired image (NBI image) based on the, specific to the cancer tumor neovascularization of the tumor by evaluating the travel state of the evaluation of the invasion depth.
Scope of claims (In Japanese)[請求項1]
内視鏡と、
前記内視鏡と共に体内に導入され、対象腫瘍が位置する対象組織に低コヒーレンス光を出射して光干渉信号を取得するマイクロ断層プローブと、
前記光干渉信号に基づいて前記対象腫瘍を含む対象組織の断層像および前記断層像内の血管における血流速情報を取得する判定部と、
を備え、
前記判定部は、前記断層像および前記血流速情報に基づいて前記対象腫瘍の深達度を判定する、
癌深達度診断システム。
[請求項2]
前記判定部は、前記断層像および前記血流速情報に基づいて、前記対象腫瘍の新生血管のうち、粘膜下層または筋層に存在する血管と連通した連通新生血管を特定し、前記連通新生血管の評価結果に基づいて前記対象腫瘍の深達度を判定する、
請求項1に記載の癌深達度診断システム。
[請求項3]
前記マイクロ断層プローブは、高周波変調された前記低コヒーレンス光を出射する、
請求項1または2に記載の癌深達度診断システム。
[請求項4]
前記血流速情報は、前記血管が押圧されて血流速が所定値以下に低下した後の血流回復に伴う血流速の立ち上がりに関する情報を含む、請求項1から3のいずれか一項に記載の癌深達度診断システム。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • OSAKA CITY UNIVERSITY
  • Inventor
  • SAEKI Souichi
  • SHIBA Masatsugu
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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