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NANO-FLUID DEVICE AND CHEMICAL ANALYSIS APPARATUS UPDATE

外国特許コード F170009068
整理番号 (AF46P001)
掲載日 2017年5月29日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2016JP081315
国際公開番号 WO 2017069256
国際出願日 平成28年10月21日(2016.10.21)
国際公開日 平成29年4月27日(2017.4.27)
優先権データ
  • 特願2015-209235 (2015.10.23) JP
発明の名称 (英語) NANO-FLUID DEVICE AND CHEMICAL ANALYSIS APPARATUS UPDATE
発明の概要(英語) This nano-fluid device is provided with a first substrate having a nanoscale groove in one surface thereof, and a second substrate for forming a nano-flow channel with the groove of the first substrate, the second substrate being provided integrally with the first substrate so that faces thereof are joined together, wherein either the first substrate or the second substrate is provided at least with a thin-walled part in a portion at a position overlapping with the nano-flow channel in plan view, and the thin-walled part deforms by pressure thereon and opens and closes the nano-flow channel.
従来技術、競合技術の概要(英語) BACKGROUND ART
Conventional, the fine space is laminar, mixing, reaction time can be shortened, the sample, a substantial reduction in the amount of reagent, and the like of the to be realized by a small device, diagnostic, and analyzing are expected to be used in the art. For example, the angle of a few centimeters on the glass substrate (microchip), or less than the depth of the groove of the several hundred µm microchannel is formed, the chemical system that has the known device.
Chemistry system 1 are integrated as one element of the device, such as a valve to control fluid can be of a device. Valve can be incorporated into a device, the micro-channels of the fluid flow direction and defines, the flow of fluid itself can be controlled.
For example, in Non-Patent Document 1, a soft polymer material such as dimethylpolysiloxane (PDMS) using a change in shape, and closing the micro flow path in which the device is described.
For example, to Patent Document 1, which is provided with a hollow portion of the glass substrate is used, the volume of the hollow portion of the fluid at the microscale can be controlled by a fluid control valve is provided which device is described.
Incidentally, in recent years, micro-scale fine space scale is reduced further having a nanoscale space has been studied.
The space having a nanoscale, smaller size than a single cell, single cell analysis device which is expected to be also used. For example, several dozen µm the size of the proteins in one cell and the like, so that a smaller size than the extension of a few hundred nm to several tens nano-space - is analyzed, the average of the multiple cells far been unable to each cell the function of the analysis becomes possible. For example, the initial cancer diagnosis or the like that is generated can be carried out is one of cancer cells is expected.
Further, the nano-scale fine space based devices, ultra-high sensitivity to the analytical tool is also expected. In this way, by using a nano-space is expanded, high sensitivity, high-speed chromatography, are countable a single molecule or molecules (of the order of counted molecules) of the immunoassay can be realized.
The influence of the surface of the dominant signal space having a nanoscale, microscale the solution properties as compared with a minute space according to the specific nature. Therefore, this unique solution properties using a new device has attracted attention.
- Several tens nm to several hundreds of such expansion of the innovative use of a nano-space is also in a device function, the fluid flowing in a microchannel to a demand control. For example, in Non-Patent Document 2, the hydrophobic nano-flow path is provided with a hydrophilic moiety, using the Laplace pressure of these interfaces are described with a stop valve.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • JAPAN SCIENCE AND TECHNOLOGY AGENCY
  • 発明者(英語)
  • KAZOE Yutaka
  • PIHOSH Yuriy
  • KITAMORI Takehiko
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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