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DEVICE FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY, AND METHOD FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY

Foreign code F170009090
File No. (S2016-0047-N0)
Posted date May 30, 2017
Country WIPO
International application number 2016JP080443
International publication number WO 2017065239
Date of international filing Oct 13, 2016
Date of international publication Apr 20, 2017
Priority data
  • P2015-203033 (Oct 14, 2015) JP
Title DEVICE FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY, AND METHOD FOR SUPPRESSING INFLAMMATION AND HYPERIMMUNITY
Abstract Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave ("pulse duration") is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.
Scope of claims [claim1]
1. Feeble pulse electric current being the device which controls the inflammation which turns on electricity to organism or organism organization, in the particular organism or organism organizing,
Electric power supply expedient
Receiving the supply of electric power, direct current electric current control means in order to impress intermittently at specified interval and,
Having,
As for the said electric current control means implication pulse duration modulation control means,
As for the said pulse duration modulation control means, the pulse wave is the rectangular wave, and, the time when peak value of the startup in 1 period of the particular pulse wave is shown ("pulse duration") is 0.1 milli-seconds or more, particular peak value is below 20V above 1.0V, as generated the pulse wave where Duty ratio of the particular pulse wave is 5.5% or more, the device which features that it is constituted.
[claim2]
2. The aforementioned inflammation it is the inflammation which it occurs with inflammation characteristic sight Cain's production, the aforementioned inflammation control, in the claim 1 which is based on the said inflammation characteristic sight Cain's production control the device of statement.
[claim3]
3. The aforementioned inflammation it is the inflammation which it occurs either CC$IL-2, IL-6, TNF-.alpha. or INF-.gamma. inflammation characteristic sight Cain's of one or more with production, in the claim 2 where the aforementioned inflammation control is based on the said inflammation characteristic sight Cain's production control the device of statement.
[claim4]
4. In the claim 3 where the aforementioned inflammation characteristic sight Cain is CC$IL-2 the device of statement.
[claim5]
5. Intermittence interval of the aforementioned direct current to be larger than 55pps and the aforementioned pulse duration from 1 milli-second either of the large claim 1-4 in one the device of statement.
[claim6]
6. In the claim 5 where the aforementioned pulse duration is 10 milli-seconds or more the device of statement.
[claim7]
7. Intermittence interval of the aforementioned direct current to be larger than 550pps and the aforementioned pulse duration from 0.1 milli-second either of the large claim 1-4 in one the device of statement.
[claim8]
8. In the claim 7 where intermittence interval of the aforementioned direct current is above 5500pps the device of statement.
[claim9]
9. Either of the claim 1-8 the remedy device which uses the device of statement for one.
[claim10]
10. Furthermore, the pad of 1 pair of the conductivity which comes in contact with the surface of the region where organism or organism organization differs
Having,
The aforementioned electric current control means are formed, in order furthermore intermittently to make feeble direct current cause between the aforementioned 1 pair pads, either of the claim 1-9 in one the device of statement.
[claim11]
11. The aforementioned inflammation, from the systemic characteristic autoimmune disease or the internal organs peculiarity autoimmune diseases either of the claim 1-10 which is based on the disease which is chosen in one the device of statement.
[claim12]
12. From the systemic characteristic autoimmune disease or the internal organs peculiarity autoimmune diseases either of the claim 1-10 which is used for remedying the inflammation which is based on the disease which is chosen in one the device of statement.
[claim13]
13. Either of the claim 1-10 which is used for the patient where the immunity inhibiter is prescribed in one the device of statement.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • KUMAMOTO UNIVERSITY
  • Inventor
  • KAI HIROFUMI
  • SHUTO TSUYOSHI
  • SUICO MARY ANN SOTEN
  • ARAKI EIICHI
  • KONDO TATSUYA
IPC(International Patent Classification)
Specified countries (WO201765239)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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