Top > Search of International Patents > ANTIBODY CAPABLE OF BINDING TO UNDIFFERENTIATED GERM CELLS OF SCOMBRIDAE FISH

ANTIBODY CAPABLE OF BINDING TO UNDIFFERENTIATED GERM CELLS OF SCOMBRIDAE FISH

Foreign code F170009268
File No. (S2016-0499-N0)
Posted date Oct 24, 2017
Country WIPO
International application number 2017JP012111
International publication number WO 2017164390
Date of international filing Mar 24, 2017
Date of international publication Sep 28, 2017
Priority data
  • P2016-060908 (Mar 24, 2016) JP
Title ANTIBODY CAPABLE OF BINDING TO UNDIFFERENTIATED GERM CELLS OF SCOMBRIDAE FISH
Abstract The present invention relates to a monoclonal antibody that specifically recognizes undifferentiated germ cells of scombridae fish, wherein the monoclonal antibody is an antibody against undifferentiated germ cells isolated from a testis or an ovary of scombridae fish. The present invention provides an antibody that can isolate undifferentiated germ cells of scombridae fish.
Scope of claims [claim1]
1. The saba course Pisces not yet differentiation reproduction cell is recognized uniquely, being the monoclonal antibody,
The monoclonal antibody, is the antibody for the not yet differentiation reproduction cell which is separated from the testes or the ovary of the saba course Pisces, the monoclonal antibody.
[claim2]
2. The saba course Pisces not yet differentiation reproduction cell is recognized uniquely, being the monoclonal antibody,
It is produced the monoclonal antibody, antibody production hybridoma TA-No.6-28 (NITE ABP-02222) or TA-No.15-1 (NITE ABP-02223) by, in claim 1 the monoclonal antibody of statement.
[claim3]
3. The not yet differentiation reproduction cell, is the initial reproduction cell, the A type spirit field cell or the oogonium, in claim 1 or 2 the monoclonal antibody of statement.
[claim4]
4. The saba course Pisces, are 1 kinds which are selected from the tuna being attached Pisces, the suma being attached Pisces, the bonito being attached Pisces and the saba being attached Pisces, either of the claim 1-3 in one section the monoclonal antibody of statement.
[claim5]
5. The surface of the saba course Pisces not yet differentiation reproduction cell is recognized uniquely, either of the claim 1-4 in one section the monoclonal antibody of statement.
[claim6]
6. Either of the claim 1-5 including the fact that it separates the not yet differentiation reproduction cell of saba course Pisces origin from the testes or the ovary of the saba course Pisces which including the not yet differentiation reproduction cell of saba course Pisces origin making use of the antibody of statement, become one section, it becomes, saba course Pisces not yet differentiation reproduction cell concentrated method.
[claim7]
7. The not yet differentiation reproduction cell which is separated from the testes or the ovary of the saba course Pisces, including the fact that it transplants to inside intraperitoneal of the landlord Pisces individual of hatching front and back, it becomes, in the differentiation induction method to the gamete of the not yet differentiation reproduction cell,
Before the transplanting, either of the claim 1-5 including the not yet differentiation reproduction cell of saba course Pisces origin in one section making use of the antibody of statement, from the testes or the ovary of the saba course Pisces which become, it separates and concentrates the saba course Pisces not yet differentiation reproduction cell,
The not yet differentiation reproduction cell which said it separates and concentrates, is transplanted to inside intraperitoneal of the landlord Pisces individual of hatching front and back
Including thing, it becomes, differentiation induction method to the gamete of the not yet differentiation reproduction cell.
[claim8]
8. The saba course Pisces which offer the not yet differentiation reproduction cell which it transplants, the landlord Pisces are different kind, in claim 7 differentiation induction method to the gamete of the not yet differentiation reproduction cell of statement.
[claim9]
9. The saba course Pisces which offer the not yet differentiation reproduction cell which it transplants, are larger-sized Pisces than the landlord Pisces, in claim 7 or 8 differentiation induction method to the gamete of the not yet differentiation reproduction cell of statement.
[claim10]
10. The landlord Pisces, are 1 kinds which are selected from the saba course Pisces, are 1 kinds where the saba course Pisces which offer the not yet differentiation reproduction cell which is transplanted are selected from the tuna, either of the claim 7-9 in one section differentiation induction method to the gamete of the not yet differentiation reproduction cell of statement.
[claim11]
11. The not yet differentiation reproduction cell which is separated from the testes or the ovary of the saba course Pisces, including the fact that it transplants to inside intraperitoneal of the landlord Pisces individual of hatching front and back, it becomes, being production method of the spermatozoon or the egg of the saba course Pisces,
Before the transplanting, either of the claim 1-5 including the not yet differentiation reproduction cell of saba course Pisces origin in one section making use of the antibody of statement, from the testes or the ovary of the saba course Pisces which become, it separates and concentrates the saba course Pisces not yet differentiation reproduction cell,
The not yet differentiation reproduction cell which said it separates and concentrates is transplanted to inside intraperitoneal of the landlord Pisces individual of hatching front and back,
The said differentiating inducing the end differentiation reproduction cell which is transplanted to the gamete, you obtain the spermatozoon or the ovum of the saba course Pisces
Including thing, it becomes, production method of the spermatozoon or the egg of the saba course Pisces.
[claim12]
12. The not yet differentiation reproduction cell which is separated from the testes or the ovary of the saba course Pisces, including the fact that it transplants to inside intraperitoneal of the landlord Pisces individual of hatching front and back, it becomes, being production method of the saba course Pisces,
Before the transplanting, either of the claim 1-5 including the not yet differentiation reproduction cell of saba course Pisces origin in one section making use of the antibody of statement, from the testes or the ovary of the saba course Pisces which become, it separates and concentrates the saba course Pisces not yet differentiation reproduction cell,
The not yet differentiation reproduction cell which said it separates and concentrates is transplanted to inside intraperitoneal of the landlord Pisces individual of hatching front and back,
It differentiates induces the not yet differentiation reproduction cell which it transplants to the gamete,
The spermatozoon and the egg which are obtained are bred
Including thing, it becomes, production method of the saba course Pisces.
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY
  • Inventor
  • ICHIDA KENSUKE
  • HAYASHI MAKOTO
  • YAZAWA RYOSUKE
  • TAKEUCHI YUTAKA
  • YOSHIZAKI GORO
IPC(International Patent Classification)
Specified countries (WO2017164390)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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