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NANOCAPSULE ACCUMULATION METHOD AND ACCUMULATION DEVICE NEW

外国特許コード F180009312
整理番号 (S2016-0761-N0)
掲載日 2018年1月24日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2017JP020883
国際公開番号 WO 2017213107
国際出願日 平成29年6月5日(2017.6.5)
国際公開日 平成29年12月14日(2017.12.14)
優先権データ
  • 特願2016-113754 (2016.6.7) JP
発明の名称 (英語) NANOCAPSULE ACCUMULATION METHOD AND ACCUMULATION DEVICE NEW
発明の概要(英語) A nanocapsule accumulation method includes: a step (C) for radiating laser light (L1) outside the wavelength region of localized surface plasmon resonance of gold nanoparticles (1) to an aqueous liquid (W) in which a plurality of nanocapsules (10) are dispersed, and thereby changing ELP2 from hydrophilic to hydrophobic by increasing the temperature of ELP2, and causing a portion of the plurality of nanocapsules (10) to aggregate; a step (D) for capturing a nanocapsule aggregate (10A) formed by the aggregation at the irradiation position of the laser light (L1); a step (E) for converting the laser light (L1) to heat through use of the gold nanoparticles (10) included in the nanocapsule aggregate (10A) and heating the liquid surrounding the nanocapsule aggregate (10A); and a step (G) for accumulating the plurality of nanocapsules (10) by a convection current generated by heating the liquid.
特許請求の範囲(英語) [claim1]
1. A plurality of nano-capsules are integrated, the integrated method of nano-capsules, each of the plurality of nano-capsules, ranging from 10 to 1 in the range of on the order of nanometers having a size of a single nanometer metal nanoparticles, metal nanoparticles and a polymer including a shell, wherein said polymer is modified on the surface of the shell, a temperature rise from hydrophobic to hydrophilic changes comprises organic molecule, wherein the integrated method of, wherein the plurality of nano-capsules dispersed in the aqueous liquid of the metal nano particles outside the wavelength range of localized surface plasmon resonance in the non-resonant light, the organic molecules of the organic molecules by raising the temperature is changed hydrophobic from hydrophilic to part of the plurality of nano-capsules and the step of aggregating, formed by aggregation of a non-aggregate nanoencapsulation resonant light at an irradiation position of the capturing step and, wherein the nano-metal nanoparticles included in the plurality of aggregates by heat is converted into a non-resonant light aggregates nanoencapsulation around said heating the liquid, the liquid is heated by a convection occurs a plurality of nano-capsules comprising the integrated circuit, the integrated method of nanocapsules.
[claim2]
2. A plurality of nano-capsules are integrated, the integrated method of microcapsules, each of the plurality of nano-capsules, ranging from 10 to 1 in the range of the order of nanometers having a size of a single nanometer metal nanoparticles, metal nanoparticles and the encapsulating polymer shell, wherein said polymer is modified on the surface of the shell, a temperature rise of from hydrophobic to hydrophilic includes organic molecules and changes to, the integrated method of, wherein the plurality of nano-capsules dispersed in a liquid organic solvent wherein the metal nano particles outside the wavelength range of localized surface plasmon resonance in the non-resonant light, the organic molecules of the organic molecules by raising the temperature is changed from hydrophobic to hydrophilic portion of the plurality of microcapsules and a step of aggregating, formed by aggregation of a non-aggregate nanoencapsulation resonant light at an irradiation position of the capturing step and, wherein the nano-metal nanoparticles included in the plurality of aggregates by heat is converted into a non-resonant light capsule The aggregate of heating the surrounding liquid, the liquid is heated by convection occurs in the plurality of nano-capsules comprising the integrated circuit, the integrated method of nanocapsules.
[claim3]
3. Wherein the step of the integrated circuit, wherein the liquid is heated to generate bubbles, the bubbles to cause convection toward each of the plurality of nano-capsules are integrated, the integrated method according to claim 1 or 2 nanocapsules.
[claim4]
4. Wherein the light is a non-resonant, included in the infrared wavelength region ranging from a laser light having a wavelength, a method of any one of claims 1-3 integrated nanocapsules.
[claim5]
5. Wherein said organic molecule is, as a temperature rises from hydrophilic to hydrophobic changes to the temperature-responsive polymer is a polymer, a method of any one of claims 1-4 integrated nanocapsules.
[claim6]
6. Wherein the polymer shell, and dendrimers, said temperature responsive polymer, (X1PGX2G)nrepresented by the polypeptide comprising amino acid sequence and, X1isoleucine or a valine, X2is the amino acid except proline, proline indicates P, g is a glycine, n is a natural number of 1 or more the integrated method according to claim 5 nanocapsules.
[claim7]
7. A plurality of nano-capsules are integrated, nanoencapsulation integrated device, each of the plurality of nano The capsule, ranging from 1 to 10 nano meters representing the range of the single nanometer metal nanoparticles having a size of the order, wherein the metal nano particles and the polymer shell is contained, and for modifying the surface of the polymer shell, due to the temperature rise is changed hydrophobic from hydrophilic to include organic molecule, wherein the integrated device includes, wherein the plurality of nano-capsules dispersed in the aqueous liquid and a holding member configured to be held, wherein the metal nano particles outside the wavelength range of localized surface plasmon resonance comprises a non-resonant light source that emits light, wherein said light source, said liquid in the non-resonance is irradiated with light, the organic molecules of the organic molecules due to the temperature rise from hydrophilic to hydrophobic is changed to a portion of the plurality of nano-aggregated, nano-capsules formed by aggregation of the aggregate at an irradiation position of the non-resonant light trapping, the nano-metal nanoparticles included in the plurality of aggregates by heat is converted into a non-resonant light capsule The heating of liquid around the aggregate, wherein the liquid is heated convection currents produced by integrating a plurality of nano-capsules, nanoencapsulation integrated device.
[claim8]
8. Integrating a plurality of nano-capsules, nanoencapsulation integrated device, each of the plurality of nano-capsules, ranging from 10 to 1 in the range of on the order of nanometers having a size of a single nanometer metal nanoparticles, metal nanoparticles and a polymer including a shell, wherein said polymer is modified on the surface of the shell, a temperature rise in the changed to be from hydrophobic to hydrophilic includes organic molecule, wherein the integrated device includes, wherein the plurality of nano-capsules dispersed in an organic solvent capable of holding a liquid and a holding member, wherein the metal nano particles outside the wavelength range of localized surface plasmon resonance comprises a non-resonant light source that emits light, wherein said light source, said liquid by irradiating said non-resonant light, the organic molecules of a temperature rise in said organic molecule is changed from hydrophobic to hydrophilic to the portion of the plurality of nanocapsules reflocculated, nano-capsules formed by aggregation of the aggregate capture non-resonant light radiating position, wherein the nano-metal nanoparticles included in the plurality of aggregates by heat is converted into a non-resonant light capsule The heating of liquid around the aggregate, wherein the liquid is heated by convection occurs in the integrated plurality of nanocapsules, nanocapsules integrated device.
[claim9]
9. Wherein said light source, wherein the metal nano particles by heat by converting a non-resonant light attached to the holding member so that bubbles are generated, by causing the bubble convection toward the plurality of nanocapsules are integrated, the integrated device according to claim 7 or 8 nanocapsules.
[claim10]
10. Wherein the non-resonant light, the wavelength region of infrared light included in the laser light having a wavelength, the integrated device to any one of claims 7-9 nanocapsules.
[claim11]
11. Wherein said organic molecule is, as a temperature rises from hydrophobic to hydrophilic polymer according to changes in the temperature-responsive polymer, any one of claims 7-10 nanocapsules of the integrated device.
[claim12]
12. Wherein the polymer shell, and dendrimers, said temperature responsive polymer, (X1PGX2G)nrepresented by the polypeptide comprising amino acid sequence and, X1isoleucine or a valine, X2is the amino acid except proline, proline indicates P, g is a glycine, n is a natural number of 1 or more according to claim 11 nanoencapsulation integrated device.
[claim13]
13. Wherein said light source, wherein the plurality of nanoencapsulation near each of the cell exists, wherein the non-resonant light generated by the irradiation of the nano-capsules included in the aggregate of the metal nano particles by heat, wherein said cells are configured so as to kill, any one of claims 7-12 nanocapsules of the integrated device.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • OSAKA PREFECTURE UNIVERSITY
  • 発明者(英語)
  • IIDA TAKUYA
  • TOKONAMI SHIHO
  • KOJIMA CHIE
  • NISHIMURA YUSHI
国際特許分類(IPC)
指定国 (WO2017213107)
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

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