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STRESS EVALUATION METHOD

Foreign code F180009335
File No. S2017-0969-N0
Posted date Mar 13, 2018
Country WIPO
International application number 2017JP005527
International publication number WO 2017141966
Date of international filing Feb 15, 2017
Date of international publication Aug 24, 2017
Priority data
  • P2016-026406 (Feb 15, 2016) JP
Title STRESS EVALUATION METHOD
Abstract Cortisol is conventionally known as a stress marker, but there are cases in which the expression thereof during stress is not constant, so cortisol is an unstable indicator. Further, cortisol does not enable distinguishing between acute stress and chronic stress. This stress evaluation method is characterized in that a state of acute stress in the test subject is determined when the 1,2,3,4-tetrahydrocyclopenta[b]indole shown in expression (1) is expressed.
Outline of related art and contending technology BACKGROUND ART
Stress may be caused by various external factors, may cause a lead to a failure and mind. Therefore, when the excessive stress entereds, it is necessary to relax the stress. However, stress, to external factors and also the individual difference of feeling, a feeling of stress for an objective evaluation method has been studied.
Patent Document 1 is, when the massage for the extent of the stress relaxation is felt to be referred to. In this case, the point that the cortisol as a stress marker has been disclosed.
Patent Document 2 is, as a stress marker, dehydroandrosterone sulfate, 17 - ketosteroid sulfate, dehydroepiandrosterone may become a stress marker is disclosed. In addition, in Patent Document 2, cortisol is, cancel the stress due to the presence of anti-stress factors, it is difficult and the quantitative index in a unified manner is mentioned as a problem to be solved.
Patent Document 3 is, as a stress marker index and dehydroepiandrosterone disclosed.
In Patent Document 4, since the stress evaluation of a Cortisol is unstable, the stress to the cortisol in a stable as an indication of the disclosed methods.
In addition, in Patent Document 5, known as a tumor marker that can be utilized as a stress marker chromogranin A, chromogranin A coffee bean extract the effect of suppressing the secretion of the disclosure of which is a point.
Scope of claims (In Japanese)[請求項1]
検査対象に、式(1)に示す1,2,3,4-テトラヒドロシクロペンタ[b]インドールが発現している場合は、急性ストレス状態であると判断することを特徴とするストレス評価方法。
[化100]
・・・(1)
[請求項2]
前記検査対象の行動異常の有無を調べる工程を有し、
前記行動異常が認められ、さらに前記1,2,3,4-テトラヒドロシクロペンタ[b]インドールが発現していない場合は、慢性ストレス状態であると判断することを特徴とするストレス評価方法。
  • Applicant
  • ※All designated countries except for US in the data before July 2012
  • KINKI UNIVERSITY
  • Inventor
  • FUNAKAMI Yoshinori
  • TAGA Atsushi
  • MITAMURA Kuniko
  • ICHIDA Seiji
IPC(International Patent Classification)
Specified countries National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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