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PROBE, EPIDERMAL ELECTRIC POTENTIAL MEASURING DEVICE, EPIDERMAL ELECTRIC POTENTIAL MEASURING METHOD, AND COSMETIC METHOD

外国特許コード F180009436
整理番号 S2018-0151-N0
掲載日 2018年7月23日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2017JP020529
国際公開番号 WO 2017204366
国際出願日 平成29年5月26日(2017.5.26)
国際公開日 平成29年11月30日(2017.11.30)
優先権データ
  • 特願2016-106831 (2016.5.27) JP
発明の名称 (英語) PROBE, EPIDERMAL ELECTRIC POTENTIAL MEASURING DEVICE, EPIDERMAL ELECTRIC POTENTIAL MEASURING METHOD, AND COSMETIC METHOD
発明の概要(英語) Provided is a probe which includes a hollow needle having an outer diameter of 0.003 to 0.4 mm and a length of 0.2 to 40 mm, and in which a distal end and a terminal end of the hollow needle are connected by means of a salt bridge. Also provided are an epidermal electric potential measuring device including said probe, an epidermal electric potential measuring method employing said epidermal electric potential measuring device, and a cosmetic method employing said epidermal electric potential measuring device.
従来技術、競合技術の概要(英語) BACKGROUND ART
The stratum corneum is the outermost layer of skin, and external foreign substances from entering the body to prevent evaporation of moisture has a barrier function. For example, one 1 of the skin disease is atopic dermatitis, inflammatory reaction to occur for failure of a barrier function, the patient's QOL (Quality Of Life: quality of life) is significantly reduced. The prevention of such diseases, treatment methods for the development, the development of tissue or cells at the level of understanding of the mechanism is demanded. However, only the skin barrier function of the change in the appearance of the analysis, it is difficult to determine, the change can be quantified and the need for the development of the system.
Skin potential, immediately below the stratum corneum of the epidermis of a potential difference formed in the thickness direction of each layer is, the barrier function by changing the nature of the failure. In this regard, the potential applied to the skin barrier function is destroyed by an electric method of treatment enhances healing of the reported (see Patent Document 1) and, according to the potential of the skin barrier function of the healing effect is believed to be due to the control, the detailed mechanism is unknown. Patent Document 1 according to the method, the body is affixed to the electrode for electrical stimulation is carried out, is directly affected by the potential with respect to the skin has been difficult.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • TOHOKU UNIVERSITY
  • 発明者(英語)
  • NISHIZAWA, Matsuhiko
  • NAGAMINE, Kuniaki
  • ABE, Yuina
  • YAMASAKI, Kenshi
国際特許分類(IPC)
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