TOP > 外国特許検索 > TRANSFORMANT, METHOD FOR PRODUCING TRANSFORMANT, AND METHOD FOR DETECTING PRESENCE OR ABSENCE OF REDUCED PHOSPHORUS COMPOUND USING TRANSFORMANT

TRANSFORMANT, METHOD FOR PRODUCING TRANSFORMANT, AND METHOD FOR DETECTING PRESENCE OR ABSENCE OF REDUCED PHOSPHORUS COMPOUND USING TRANSFORMANT NEW

外国特許コード F180009495
整理番号 S2016-0948-C0
掲載日 2018年11月1日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2017JP027588
国際公開番号 WO 2018042987
国際出願日 平成29年7月31日(2017.7.31)
国際公開日 平成30年3月8日(2018.3.8)
優先権データ
  • 特願2016-170317 (2016.8.31) JP
発明の名称 (英語) TRANSFORMANT, METHOD FOR PRODUCING TRANSFORMANT, AND METHOD FOR DETECTING PRESENCE OR ABSENCE OF REDUCED PHOSPHORUS COMPOUND USING TRANSFORMANT NEW
発明の概要(英語) The purpose of the present invention is to provide a transformant, which has an excellent sealing effect and can be prepared by a simple process, a method for producing the transformant and a method for detecting the presence or absence of a reduced phosphorus compound with the use of the transformant. For this purpose, the transformant according to the present invention lacks the function of a gene encoding a phosphoric acid transporter protein and the function of a gene encoding a phosphate transporter protein and carries a gene, said gene encoding a hypophosphorous acid transporter protein, transferred thereinto.
従来技術、競合技術の概要(英語) BACKGROUND ART
In recent years, can be applied to a wide variety of applications to produce the recombinant organism.Genetically engineered organism is made, for example, oral vaccine, or, for the purpose of improvement of the environment is expected to be used.
On the other hand, in order to actually use the genetically engineered biological, some condition.As one of conditions 1, only in a limited location and growth, the growth in biological genetic recombination cannot be other than the location (in other words, the high confinement effects genetically engineered biological) needs to be made.If such a transgenic organism, the naturally occurring biological genetic recombination even if the leakage, the transgenic organism cannot be grown in a naturally occurring, genetically engineered biological nature by the contamination can be prevented.
In this way for making such transgenic organism a variety of methods have been developed and, as such a method, an organism (i) is introduced into the toxic gene, the gene for the desired time has passed and the toxicity of a method for killing the organism (suicide switch (kill switch)), and, the growth from an organism (ii) mandatory to live are deleted in the ability to synthesize a compound, supplied from the outside of the organism to survive by nutrients (auxotrophy) method can be exemplified.
However, (i) and (ii) the above method, the encapsulation effect is not sufficient, the high confinement effects further development of the method has been desired.
Under such circumstances, (iii) relative to a, in the natural world does not exist for a method of providing nutritional auxotrophy (synthetic auxotrophic (synthetic auxotrophy) ) is, the newly developed. (Iii) as a concrete example of the disclosed method, non-patent document 1 can be exemplified.In Non-Patent Document 1, does not exist in the natural world and artificially synthesized under an environment in which the amino acid can be grown in the presence of E. coli and a method of fabricating described.In this method, a large number of gene mutations in the E. coli by the introduction, purpose and produced in E. coli.Then, in the method of (iii), for example, 1011 genetically engineered biological nature of the assumed leaking out of the case, naturally the number of genetically engineered biological can survive, and the number 0.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • HIROSHIMA UNIVERSITY
  • 発明者(英語)
  • HIROTA RYUICHI
  • KURODA AKIO
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG

PAGE TOP

close
close
close
close
close
close