外国特許コード F180009567
整理番号 S2017-0528-C0
掲載日 2018年11月5日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP009499
国際公開番号 WO 2018168766
国際出願日 平成30年3月12日(2018.3.12)
国際公開日 平成30年9月20日(2018.9.20)
  • 特願2017-047982 (2017.3.14) JP
発明の概要(英語) Through the present invention, three-dimensional coordinates of a tracking object moving in an irradiation object can be calculated from fluoroscopic X-ray images captured and acquired from various angles in a single fluoroscopic X-ray device mounted to a radiation therapy apparatus. The three-dimensional coordinates of the tracking object are calculated on a straight tracking object presence line connecting an X-ray generating device for fluoroscopy and the position in an X-ray plane detector of the tracking object on the fluoroscopic X-ray image acquired by the X-ray generating device for fluoroscopy and the X-ray plane detector, and using line segment information included in a movement region of the tracking object set in advance (S104).
従来技術、競合技術の概要(英語) BACKGROUND ART
Such as a cancer patient to radiation such as X-ray or a charged particle radiation therapy to an affected part is known.This treatment in recent years, more normal tissue to radiation can be suppressed, resulting in localized treating the affected area immediately before the treatment of the patient anatomical information of the location of the affected site and its surrounding tissue in an attempt to accurately grasp the information has been carried out.Immediately before the treatment of the patient's body in order to obtain anatomical information, the radiation treatment device provided in the radiation from the various angles for an affected part with the rotating gantry mounted on the X-ray imaging apparatus using a perspective view of a cone beam CT (CBCT) CBCT imaging apparatus is used.The CBCT imaging apparatus to the patient while rotating the gantry so as to surround the X-ray photographed intermittently perspective, X-ray image acquired by the perspective three-dimensional reconstruction 3 can create a three-dimensional image 3.CBCT image is acquired of the patient treatment plan is compared to the CT image, when a treatment plan and the position of the bone and organ of the affected area and the vicinity thereof are coincident with each other and the determination of whether the patient so as to match the two positions used for alignment.It should be noted that, in the case of the affected area of cancer the patient is being treated is mainly means a tumor.
In the radiation therapy to the patient's body, and the subject is breathing by the tumor may move.In such a case, the entire movement range of the tumor is considered a method of applying radiation to the radiation dose to normal tissue is increased.Normal tissue dose of radiation to the tumor as much as possible can be applied in order to concentrate the radiation, current, the tracked object is previously embedded in the vicinity of the tumor (a metallic marker) is a perspective view from the position in the photographed image in the X-ray is measured, such as X-ray image on the perspective that it tracks the location of the tumor is estimated from the position of the object, the tracked object in a predetermined position only when the phase of the respiration of the tumor is irradiated with radiation to the normal tissue can be reduced by the irradiation method is adopted.Generally the phase of the respiration rate 1 as a feature in which the movement of the breathing cycle phase is reduced and a long residence time in the expiration phase, the above-described radiation treatment when the breathing condition this exhalation phase is irradiated with radiation is employed.Therefore, a radiation treatment plan in the planning CT is used for a treatment plan phase state of the patient's breath by breath produced, captured in a state that the image is being used.
CBCT is captured just prior to the treatment described above is, in the presence of a tumor in the body trunk of the periphery of the bone and organ tumor or breath motion, CBCT image fluctuation is obtained.Moving the image fluctuation and the exact location of a tumor or organ cannot be identified, the treatment planning CT cannot be compared.In order to solve this problem the patient's body to track the movement of infrared markers, movement of the diaphragm or within the X-ray image at the time of shooting on the CBCT a perspective view of the phase of the respiration can be monitored to determine, when a treatment plan at the time of photographing the same respiratory phase X-ray image subtraction using only the three-dimensional reconstruction 3 can reduce the influence caused by the motion blur and the image quality of the acquired CBCT image is a method.CBCT image for obtaining such 4 imaging techniques may be a three-dimensional CBCT (4D-CBCT) imaging technique has been developed in recent years are referred to.However, the above-described motion of the diaphragm and the body motion that may occur out of the correlation has been reported, in the case of the diaphragm at the time of imaging the imaging region on the CBCT X-ray image does not appear in the perspective view in some cases.More, exactly the same as at the patient's treatment plan to know the state of the respiratory phase in the vicinity of the tumor or directly to the motion of the tracked object 3 it is desirable that the three-dimensional tracking.In recent years, as described in Patent Document 1 is a perspective view of the axis perpendicular to the X-ray imaging apparatus 2 with the vicinity of the tumor in the CBCT imaging apparatus tracking the object 3 embedded in track 3 of the three-dimensional CBCT imaging the tumor in three-dimensional position measurement technique has been developed.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • 発明者(英語)
  • FUJII Takaaki
  • TAKAO Seishin
  • MIYAMOTO Naoki
  • MATSUURA Taeko
  • UMEGAKI Kikuo