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AIRWAY VENTILATION STATE CALIBRATION SYSTEM AND SYSTEM FOR PREDICTING AIRWAY DEFORMATION DURING SLEEP NEW

外国特許コード F180009571
整理番号 (S2017-0362-N0)
掲載日 2018年11月5日
出願国 世界知的所有権機関(WIPO)
国際出願番号 2018JP007780
国際公開番号 WO 2018159759
国際出願日 平成30年3月1日(2018.3.1)
国際公開日 平成30年9月7日(2018.9.7)
優先権データ
  • 特願2017-038358 (2017.3.1) JP
発明の名称 (英語) AIRWAY VENTILATION STATE CALIBRATION SYSTEM AND SYSTEM FOR PREDICTING AIRWAY DEFORMATION DURING SLEEP NEW
発明の概要(英語) A nasal cavity model generating unit (41) extracts pixels having a pixel density value in a specific range from three-dimensional image data of a nasal cavity of a subject contained in DICOM data (21), and generates a nasal cavity model (50), which is a three-dimensional shape model of the nasal cavity, on the basis of three-dimensional image data configured using the extracted pixels. A nasal cavity resistance value calculating unit (42) obtains a nasal cavity resistance value (51) by means of fluid analysis employing the nasal cavity model (50) generated by the nasal cavity model generating unit (41). An adjusting unit (43) adjusts the pixel density value range to be extracted in order for the nasal cavity model generating unit (41) to generate the nasal cavity model (50), in such a way that the nasal cavity resistance value (51) obtained by the nasal cavity resistance value calculating unit (42) and a nasal cavity resistance value (52) measured by means of a nasal cavity ventilation meter coincide.
従来技術、競合技術の概要(英語) BACKGROUND ART
Obstructive sleep apnea syndrome (OSAS; Obstructive Sleep Apnea Syndrome) is, upper airway obstruction during the sleep disordered breathing occurs, adversely affecting various systemic disease of the respiratory system.Obstructive sleep apnea syndrome (hereinafter, simply, referred to as sleep apnea syndrome) is, not obtained sufficient sleep at night during the day so as to contribute to driver drowsiness can be excessive, significant attention has been paid as the cause of a traffic accident.
Diagnosis of sleep apnea syndrome than the conventional method has been proposed.For example, in Non-Patent Document 1, the three-dimensional CT image 3 based on a fluid model of the upper airways constructed on the computer, which uses a fluid model analysis is performed, the diagnosis of sleep apnea syndrome is a method has been proposed.According to this method, the pressure distribution of the upper respiratory tract, based on the velocity distribution of air, air to some extent the failure, can be narrowed down.
Sleep apnea syndrome, adult onset of the frequency 4%, in the case of the child regardless of age at puberty from infancy 2% as referred to, is the relatively high frequency of such diseases.Nevertheless, sleep apnea syndrome, an effective method for identifying the site of origin is not established yet, a sufficient treatment outcome was not obtained at present.Non-Patent Document 1 is proposed in the method, sleep apnea syndrome is effective to narrow down the site of origin of a few techniques that, for such problems as the following, the treatment result is obtained is not always effective is not limited thereto.
(1) The simulation model of the upper respiratory tract, does not deform as a rigid body are modeled.For this reason, in consideration of the elastic deformation of the upper respiratory tract can be realized because the fluid analysis, of the upper airway occlusion cannot be reproduced.
(2) Are modeled only in the upper, the underlying causes of sleep apnea syndrome is often at the site of the upper respiratory tract and the surrounding tissue is not modeled, the deformation of the tissue in the vicinity of the upper respiratory tract cannot be reproduced.Therefore, the person who performs the diagnosis, the fundamental cause of the sites from the analysis result of the fluid only an indirect estimation.
For example, sleep apnea syndrome as those as a main site of origin, at the elevation of the tongue due to gravity-drop is due to the narrowing of the upper airways.However, the technique disclosed in Non-Patent Document 1 is, of the upper airway tissue surrounding the tongue is not modeled, with a drop of the tongue due to gravity of the upper airway narrowing cannot be reproduced by simulation.For this reason, in this technique, the cause of sleep apnea syndrome, depression of the tongue by the action of gravity at the elevation direction of the upper respiratory tract caused by the narrowing, it is difficult to identify.
(3) Fluid analysis using a simulation model assumed in the flow of air along the way in the upper direction and, in an actual bi-directional flow of the air breathing (breath intake changes in a cycle) and the arrangements are different from each other.For this reason, according to the aspects of breathing of the actual flow of fluid the upper respiratory tract cannot be reproduced.
Therefore, for the disease of the respiratory system, for example, to Patent Document 1, a good treatment result can be more reliably diagnosing the device, the diagnostic system, diagnostic method and a program is disclosed.
  • 出願人(英語)
  • ※2012年7月以前掲載分については米国以外のすべての指定国
  • KAGOSHIMA UNIVERSITY
  • 発明者(英語)
  • IWASAKI TOMONORI
  • YAMASAKI YOUICHI
国際特許分類(IPC)
指定国 National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
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