COMPOSITION FOR PROMOTING PRODUCTION OF IMMUNOSTIMULATORY FACTOR
|Posted date||Nov 20, 2018|
|International application number||2017JP027638|
|International publication number||WO 2018025793|
|Date of international filing||Jul 31, 2017|
|Date of international publication||Feb 8, 2018|
|Title||COMPOSITION FOR PROMOTING PRODUCTION OF IMMUNOSTIMULATORY FACTOR|
|Abstract||This composition, for promoting immunostimulatory factor production, contains the genomic double-stranded RNA of a plant-derived endornavirus, and can prevent and improve a variety of diseases such as viral diseases, cancer and multiple sclerosis.|
|Outline of related art and contending technology||
Effective treatment of viral diseases in general has not been established, the normal, corresponding to each of the viral disease therapy has been employed. For example, interferon therapy for hepatitis C or the like, with respect to the specific influenza viral diseases (Tamiflu, Relenza and the like) of the anti-viral drug administration has been performed. However, the risk of side effects, from the viewpoint of cost, preventing continuous interferon therapy for the purpose of usage is difficult. In addition, the current anti-viral agent may be synthetic or a low molecular compound and an active component, from the viewpoint of cost and the like, also can be used continuously for the purpose of preventing difficult.
With respect to cancer, such as DNA synthesis acts in order to prevent the proliferation of cancer cells and anti-cancer therapy, activate an inhibit the growth of cancer cells for the purpose of drug therapy such as interferon therapy and has been performed. However, the risk of side effects from the viewpoint of cost or the like, for the purpose of preventing continuous interferon therapy is difficult to use. In addition, the current anti-cancer agent, usually a low molecular weight compound are combined, and the active ingredients of the antibody or the like, from the viewpoint of cost and the like, also can be used continuously for the purpose of preventing difficult.
Also for multiple sclerosis, viral diseases, cancer or the like in the same manner, a low-molecular compound, such as interferon treatment is performed, the risk of side effects, from the viewpoint of cost and the like, can be used continuously for the purpose of preventing difficult.
In this manner, viral diseases, cancer, multiple sclerosis and the like of a variety of diseases and is applicable to a broad range, the prevention of these diseases can be used for further (i.e. to reduce the risk of side effects, low cost) for the treatment is not known.
On the other hand, the end luna virus, plant, particularly of green peppers, such as rice plant edible intake routine is present have been reported (Non-Patent Document 1, Non-Patent Document 2 or the like). Certain RNA virus, MDA5, such as through a signal transmission path through the RIG-I interferon induced production, as a result, inside of the living organism is called dimethylarninopropyl immunopotentiators. However, the association of viral diseases end luna virus is not known.
|Scope of claims||
(In Japanese)請求の範囲 [請求項1]
|IPC(International Patent Classification)||
National States: AE AG AL AM AO AT AU AZ BA BB BG BH BN BR BW BY BZ CA CH CL CN CO CR CU CZ DE DJ DK DM DO DZ EC EE EG ES FI GB GD GE GH GM GT HN HR HU ID IL IN IR IS JO JP KE KG KH KN KP KR KW KZ LA LC LK LR LS LU LY MA MD ME MG MK MN MW MX MY MZ NA NG NI NO NZ OM PA PE PG PH PL PT QA RO RS RU RW SA SC SD SE SG SK SL SM ST SV SY TH TJ TM TN TR TT TZ UA UG US UZ VC VN ZA ZM ZW
ARIPO: BW GH GM KE LR LS MW MZ NA RW SD SL SZ TZ UG ZM ZW
EAPO: AM AZ BY KG KZ RU TJ TM
EPO: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
OAPI: BF BJ CF CG CI CM GA GN GQ GW KM ML MR NE SN ST TD TG
Contact Information for " COMPOSITION FOR PROMOTING PRODUCTION OF IMMUNOSTIMULATORY FACTOR "
- Kyoto University Office of Society-Academia Collaboration for Innovation
- URL: http://www.saci.kyoto-u.ac.jp/
- Address: 36-1, Yoshida-honmachi, Sakyo-ku, Kyoto-shi, Kyoto, JAPAN , 606-8501
- Fax: +81-75-753-7591